Browsing Physiology (Scholarly Publications) by Title
Now showing items 41-60 of 136
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The EBI2 signalling pathway plays a role in cellular crosstalk between astrocytes and macrophages
(2016)EBI2 is a G protein-coupled receptor activated by oxysterol 7α, 25-dihydroxycholesterol (7α25HC) and regulates T cell-dependant antibody response and B cell migration. We recently found EBI2 is expressed in human astrocytes, ... -
Effect of body tilt angle on fatigue and EMG activities in lower limbs during cycling
(2010)This study compared the rate of fatigue and lower limb EMG activities during high-intensity constantload cycling in upright and supine postures. Eleven active males performed seven cycling exercise tests: one upright graded ... -
Effect of body tilt on calf muscle performance and blood flow in humans
(American Physiological Society, 2005)To explore the effect of posture on muscle performance, we tested the effects of body tilt angle on the strength, endurance, and fatigue of, and blood flow into, the plantar flexors. Human subjects were fixed to a tilt ... -
The effect of externally generated loading on predictive grip force modulation.
(2007)A characteristic of skilled movement is the ability of the CNS to predict the consequences of motor commands. When we lift an object there is an anticipatory increase in grip force that prevents a grasped object from ... -
Effect of low recumbent angle on cycling performance, fatigue and VO2 kinetics.
(2013)Purpose: This study aimed to examine the effect of the degree of inclination from upright to supine postures on cycling performance, fatigue, and oxygen uptake (V˙O(2)) kinetics. Methods: In experiment 1, 10 subjects ... -
Effect of type 2 diabetes on the dynamic response characteristics of leg vascular conductance during exercise
(2011)In this study we tested the hypothesis that type 2 diabetes impairs the dynamic response of leg vascular conductance (LVC) during exercise. LVC (leg blood flow/mean arterial pressure) responses were studied during intermittent ... -
Elucidating the complex organization of neural micro-domains in the locust Schistocerca gregaria using dMRI
(2021)To understand brain function it is necessary to characterize both the underlying structural connectivity between neurons and the physiological integrity of these connections. Previous research exploring insect brain ... -
Enhanced motor learning following task-concurrent dual transcranial direct current stimulation.
(2013)OBJECTIVE: Transcranial direct current stimulation (tDCS) of the primary motor cortex (M1) has beneficial effects on motor performance and motor learning in healthy subjects and is emerging as a promising tool for motor ... -
Exploring Sex-Related Differences in Microglia May Be a Game-Changer in Precision Medicine
(2022)One area of microglial biology that has been relatively neglected until recently is sex differences and this is in spite of the fact that sex is a risk factor in several diseases that are characterized by neuroinflammation ... -
The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation.
(2012)Background: Several factors contribute to the deterioration in synaptic plasticity which accompanies age and one of these is neuroinflammation. This is characterized by increased microglial activation associated with ... -
Fingolimod Attenuates Splenocyte-Induced Demyelination in Cerebellar Slice Cultures
(2014)The family of sphingosine-1-phosphate receptors (S1PRs) is G-protein-coupled, comprised of subtypes S1PR1-S1PR5 and activated by the endogenous ligand S1P. The phosphorylated version of Fingolimod (pFTY720), an oral therapy ... -
Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes
(2016)Check TCD e-journals(opens in a new window)|View at Publisher| RIS export | Download | Add to List | More... Journal of Neuroinflammation Volume 13, Issue 1, February 08, 2016, Article number 31 Open ... -
From Mechanisms to Analgesia: Towards the Use of Non-Invasive Neuromodulation for Pain Relief in the Clinic
(Intech Open, 2020)The use of electricity for analgesic effects has a long history and yet currently neuromodulation devices based on electrical stimulation are typically restricted to being a last resort intervention for pain patients after ...