Browsing Pharmacy and Pharmaceutical Sciences by Author "SANTOS-MARTINEZ, MARIA"
Now showing items 1-13 of 13
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Analysis of platelet function: role of microfluidics and nanodevices
RADOMSKI, MAREK; MEDINA MARTIN, CARLOS; SANTOS-MARTINEZ, MARIA (2011)Platelet aggregation is essential for vascular haemostasis and thrombosis. To improve the therapy of arterial thrombotic disorders and identify novel therapeutic targets it is imperative to study basic mechanisms of platelet ... -
CdTe quantum dots induce activation of human platelets: Implications for nanoparticle hemocompatibility
PRINA MELLO, ADRIELE; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS; VOLKOV, YURI (2015) -
Chondroitin-based nanoplexes as peptide delivery systems--Investigations into the self-assembly process, solid-state and extended release characteristics.
TAJBER, LIDIA; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS (2015) -
Differential Inhibition of Tumor Cell-Induced Platelet Aggregation by Nicotinate Aspirin Prodrug (ST0702) and Aspirin.
SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS (2012) -
Exploring the assembly process and properties of novel crosslinker-free hyaluronate-based polyelectrolyte complex nanocarriers
TAJBER, LIDIA; SANTOS-MARTINEZ, MARIA; CORRIGAN, OWEN; UMERSKA, ANITA MONIKA; PALUCH, KRZYSZTOF; MEDINA MARTIN, CARLOS (2012) -
Mechanisms of aggregation inhibition by aspirin and nitrate-aspirin prodrugs in human platelets
RADOMSKI, MAREK; SANTOS-MARTINEZ, MARIA (2012)OBJECTIVES: Aspirin is the mainstay of anti-platelet therapy in the secondary prevention of cardiovascular disease. However, problems with aspirin safety and resistance demand clinical strategies based on multiple ... -
Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK-MMP-9 pathway.
SANTOS-MARTINEZ, MARIA; RADOMSKI, MAREK; MEDINA MARTIN, CARLOS (2014) -
Nanoparticles: pharmacological and toxicological significance
RADOMSKI, MAREK; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS; CORRIGAN, OWEN (2007) -
Pharmacological and toxicological effects of co-exposure of human gingival fibroblasts to silver nanoparticles and sodium fluoride
RADOMSKI, MAREK; SANTOS-MARTINEZ, MARIA (2014)BACKGROUND: Silver nanoparticles (AgNPs) and fluoride (F) are pharmacological agents widely used in oral medicine and dental practice due to their anti-microbial/anti-cavity properties. However, risks associated with ... -
Pharmacological characterization of nanoparticle-induced platelet microaggregation using quartz crystal microbalance with dissipation: comparison with light aggregometry
RADOMSKI, MAREK; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS (2015) -
PKCä Mediates Platelet-Induced Breast Cancer Cell Invasion
MEDINA MARTIN, CARLOS; SANTOS-MARTINEZ, MARIA (2006) -
Platelet aggregation induced by Caco-2 cells: regulation by matrix metalloproteinase-2 and adenosine diphosphate
RADOMSKI, MAREK; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS (2006)Formation of tumor cell-platelet aggregates facilitates hematogenous metastases. However, molecular mechanisms implicated in tumor cell-induced platelet aggregation (TCIPA) in colon cancer are unclear. To investigate ... -
Self-assembled hyaluronate/protamine polyelectrolyte nanoplexes: synthesis, stability, biocompatibility and potential use as peptide carriers
TAJBER, LIDIA; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS; CORRIGAN, OWEN (2014)This work investigates a new type of polyelectrolyte complex nanocarrier composed of hyaluronic acid (HA) and protamine (PROT). Small (approximately 60 nm) and negatively charged nanoparticles (NPs) with a polydispersity ...