Browsing RSS Feeds by Author "GALLAGHER, LOUISE"
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Abnormal functional connectivity in autism spectrum disorder is associated with disrupted white matter microstructural organisation
GALLAGHER, LOUISE (2013)Disruption of structural and functional neural connectivity has been widely reported in Autism Spectrum Disorder (ASD) but there is a striking lack of research attempting to integrate analysis of functional and structural ... -
Artificial milk-feeding women's views of their feeding choice in Ireland
BEGLEY, CECILY; GALLAGHER, LOUISE; CARROLL, MARGARET; CLARKE, MICHAEL (2015)Objective: despite the well-documented benefits of breast feeding to both mother and child, breast-feeding initiation rates in Ireland are the second lowest in Europe. This study set out to explore the views of women from ... -
Assessing Problem based learning in Child and Adolescent Psychiatry at the Trinity College Dublin Ireland
GILL, MICHAEL; GALLAGHER, LOUISE; FRODL, THOMAS (2012) -
The autism brain imaging data exchange: Towards a large-scale evaluation of the intrinsic brain architecture in autism
GALLAGHER, LOUISE (2014)Autism spectrum disorders (ASDs) represent a formidable challenge for psychiatry and neuroscience because of their high prevalence, lifelong nature, complexity and substantial heterogeneity. Facing these obstacles requires ... -
Bio-collections in autism research.
GALLAGHER, LOUISE (2017) -
Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders
MERIKANGAS, ALISON; GALLAGHER, LOUISE; BOLSHAKOVA, NADIA (2014)Rare copy-number variation (CNV) is an important source of risk for autism spectrum disorders (ASDs). We analyzed 2,446 ASD-affected families and confirmed an excess of genic deletions and duplications in affected versus ... -
Dissociation in performance of children with ADHD and autism on a task of sustained attention
JOHNSON, KATHERINE; ROBERTSON, IAN; GALLAGHER, LOUISE; GILL, MICHAEL; BELLGROVE, MARK; FITZGERALD, MICHAEL (2007)Attention deficit hyperactivity disorder (ADHD) and autism are two neurodevelopmental disorders associated with prominent executive dysfunction, which may be underpinned by disruption within fronto-striatal and fronto-parietal ... -
Dissociation in performance of children with ADHD and high-functioning autism on a task of sustained attention.
GALLAGHER, LOUISE; GILL, MICHAEL; JOHNSON, KATHERINE ANNE; ROBERTSON, IAN (Elsevier, 2007)Attention deficit hyperactivity disorder (ADHD) and autism are two neurodevelopmental disorders associated with prominent executive dysfunction, which may be underpinned by disruption within fronto-striatal and fronto-parietal ... -
Enhancing studies of the connectome in autism using the autism brain imaging data exchange II
GALLAGHER, LOUISE (2017)The second iteration of the Autism Brain Imaging Data Exchange (ABIDE II) aims to enhance the scope of brain connectomics research in Autism Spectrum Disorder (ASD). Consistent with the initial ABIDE effort (ABIDE I), that ... -
Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders.
CORVIN, AIDEN; HERON, ELIZABETH; GILL, MICHAEL; DONOHOE, GARY; ANNEY, RICHARD; GALLAGHER, LOUISE; MORRIS, DEREK; TROPEA, DANIELA; KENNY, ELAINE (2014) -
Exploration of empirical Bayes hierarchical modeling for the analysis of genome-wide association study data.
GILL, MICHAEL; HERON, ELIZABETH ANN; GALLAGHER, LOUISE (2011)In the analysis of genome-wide association (GWA) data, the aim is to detect statistical associations between single nucleotide polymorphisms (SNPs) and the disease or trait of interest. These SNPs, or the particular regions ... -
Functional and structural connectivity of frontostriatal circuitry in Autism Spectrum Disorder.
BALSTERS, JOSHUA; GALLAGHER, LOUISE; MCGRATH, JANE (2013)Abnormalities in frontostriatal circuitry potentially underlie the two core deficits in Autism Spectrum Disorder (ASD); social interaction and communication difficulties and restricted interests and repetitive behaviors. ... -
Functionality of promoter microsatellites of arginine vasopressin receptor 1A (AVPR1A): implications for Autism.
ANNEY, RICHARD JAMES LEON; GILL, MICHAEL; GALLAGHER, LOUISE (BIOMED CENTRAL, 2011)Background: Arginine vasopressin (AVP) has been hypothesized to play a role in aetiology of autism based on a demonstrated involvement in the regulation of social behaviours. The arginine vasopressin receptor 1A gene (AVPR1A) ... -
Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders.
GILL, MICHAEL; GALLAGHER, LOUISE; ANNEY, RICHARD; KENNY, ELAINE (2011)Recent genome-wide association studies (GWAS) have implicated a range of genes from discrete biological pathways in the aetiology of autism. However, despite the strong influence of genetic factors, association studies ... -
A genome-wide linkage and association scan reveals novel loci for autism.
GILL, MICHAEL; GALLAGHER, LOUISE (Nature, 2009)Although autism is a highly heritable neurodevelopmental disorder, attempts to identify specific susceptibility genes have thus far met with limited success 1. Genome-wide association studies (GWAS) using half a million ... -
A genomewide scan for common alleles affecting risk for autism.
ANNEY, RICHARD; GALLAGHER, LOUISE; GILL, MICHAEL; BOLSHAKOVA, NADIA; SEGURADO, RICARDO; HERON, ELIZABETH; MCGRATH, JANE; TANSEY, KATHERINE; BRENNAN, SEAN; MERIKANGAS, ALISON; MERIKANGAS, ALISON KATHLEEN (2010)Although autism spectrum disorders (ASDs) have a substantial genetic basis, most of the known genetic risk has been traced to rare variants, principally copy number variants (CNVs). To identify common risk variation, the ... -
A genomewide scan for common alleles affecting risk for autism.
SEGURADO, RICARDO; ANNEY, RICHARD JAMES LEON; MC GRATH, JANE; BOLSHAKOVA, NADEZDA; GILL, MICHAEL; HERON, ELIZABETH ANN; TANSEY, KATHERINE; GALLAGHER, LOUISE (Oxford University Press, 2010)Although autism spectrum disorders (ASDs) have a substantial genetic basis, most of the known genetic risk has been traced to rare variants, principally copy number variants (CNVs). To identify common risk variation, the ... -
Individual common variants exert weak effects on the risk for autism spectrum disorderspi.
ANNEY, RICHARD; MERIKANGAS, ALISON; HERON, ELIZABETH; GILL, MICHAEL; GALLAGHER, LOUISE (2012)While it is apparent that rare variation can play an important role in the genetic architecture of autism spectrum disorders (ASDs), the contribution of common variation to the risk of developing ASD is less clear. To ... -
Mental health problems in children with prader-willi syndrome.
GALLAGHER, LOUISE (2012)BACKGROUND: Prader-Willi Syndrome (PWS) is a genetically determined neurodevelopmental disorder, which occurs in approximately one in 22000 births. AIMS: This study aimed to investigate psychiatric characteristics of ... -
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
GALLAGHER, LOUISE; GILL, MICHAEL (2017)