Browsing Anatomy by Subject "Beta-Hydroxybutyrate"
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The Effects of Glucose Deprivation and Ketone Supplementation on the Growth and Function of Neural Stem and Neuronal Precursor Cells
(Trinity College Dublin. School of Medicine. Discipline of Anatomy, 2023)The cellular and phenotypic effects that carbohydrate restriction have on brain development are unclear. Ketone bodies become a primary energy source in periods of prolonged glucose deprivation, due to dieting, strenuous ... -
The metabolic determinants of the response to ketone bodies in SH-SY5Y neuroblastoma cells
(Trinity College Dublin. School of Medicine. Discipline of Anatomy, 2020)Neuroblastoma (NB) is a childhood malignancy of the sympathetic nervous system. Its mutual neoplastic and neurodevelopmental underpinnings are characterised by an excessive glucose demand as a hallmark of a high proliferative ...