Search
Now showing items 1-10 of 331
The protein interacting with C-kinase (PICK1) interacts with and attenuates parkin-associated endothelial-like (PAEL) receptor-mediated cell deat
(2014)
The parkin-associated endothelial-like receptor (PAELR, GPR37) is an orphan G protein-coupled receptor that interacts with and is degraded by parkin-mediated ubiquitination. Mutations in parkin are thought to result in ...
Habitual physical activity and cardiometabolic risk factors in adults with cerebral palsy
(2014)
Adults with cerebral palsy (CP) are known to participate in reduced levels of total physical activity. There is no information available however, regarding levels of moderate-to-vigorous physical activity (MVPA) in this ...
Patients over 65 years are assigned lower ECOG PS scores than younger patients, although objectively measured physical activity is no different
(2014)
Objectives
The Eastern Cooperative Group Performance Status (ECOG PS) is a widely used standard functional classification in oncology practice, the verbal descriptors of which refer to physical activity (PA). Little is ...
Interplay Between Childhood Physical Abuse and Familial Risk in the Onset of Psychotic Disorders.
(2014)
Background
: Childhood abuse is considered one of the main
environmental risk factors for the development of psychotic
symptoms and disorders. However, this association could
be due to genetic factors influencing ...
Neurotransmitter receptor and time dependence of the synaptic plasticity disrupting actions of Alzheimer's disease Aß in vivo.
(2014)
Many endogenous factors influence the time course and extent of the detrimental effects of amyloid β-protein (Aβ) on synaptic function. Here, we assessed the impact of varying endogenous glutamatergic and cholinergic ...
Multiple norovirus infections in a birth cohort in a Peruvian peri-urban community.
(2014)
Human noroviruses are among the most common enteropathogens globally, and are a leading cause of infant diarrhea in developing countries. However, data measuring the impact of norovirus at the community level are ...
DIFFERENTIAL INTERACTIONS OF ANTIRETROVIRAL AGENTS WITH LXR, ER AND GR NUCLEAR RECEPTORS - POTENTIAL CONTRIBUTING FACTORS OF ADVERSE EVENTS
(2014)
BACKGROUND AND PURPOSE:
Antiretroviral (ARV) drugs activate pregnane X receptors and constitutive androstane receptors, increasing the risk of drug interactions due to altered drug metabolism and disposition. The closely ...
The prevalence of respiratory symptoms among mushroom workers in Ireland
(2014)
BACKGROUND:
Respiratory conditions such as asthma, bronchitis, hypersensitivity pneumonitis and upper airways symptoms have been ascribed to fungal exposures. Mushroom workers may be at risk of these as a consequence. ...