Browsing School of Medicine by Author "Rana, Batika M.J."
Now showing items 1-2 of 2
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MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity.
Fallon, Padraic; Knolle, Martin D.; Chin, Shau Bing; Rana, Batika M.J.; Englezakis, Alexandros; Nakagawa, Rinako; Git, Anna; McKenzie, Andrew N.J. (2018)Group-2 innate lymphoid cells (ILC2) play critical roles in the initiation and maintenance of type-2 immune responses, predominantly through their production of the type-2 cytokines IL-5, IL-9, and IL-13. ILC2 are essential ... -
Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells
Fallon, Padraic; Halim, Timotheus Y.F.; Rana, Batika M.J.; Walker, Jennifer; Kerscher, Bernhard; Knolle, Martin D.; Jolin, Helen E.; Serrao, Eva M.; Haim-Vilmovsky, Liora; Teichmann, Sarah A.; Rodewald, Hans-Reimer; Botto, Marina; Vyse, Timothy J.; Li, Zhi; Withers, David R.; McKenzie, Andrew N.J. (2018)The local regulation of type 2 immunity relies on dialog between the epithelium and the innate and adaptive immune cells. Here we found that alarmin-induced expression of the co-stimulatory molecule OX40L on group 2 innate ...