Browsing School of Medicine by Author "QUINN, EMMA"
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Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function.
QUINN, EMMA; KENNY, ELAINE; CORVIN, AIDEN; GILL, MICHAEL; MORRIS, DEREK (2010)Investigators have linked rare copy number variation (CNVs) to neuropsychiatric diseases, such as schizophrenia. One hypothesis is that CNV events cause disease by affecting genes with specific brain functions. Under these ... -
Fine mapping of ZNF804A and genomime-wide significant evidence for it's involvement in Schizophrenia and bipolar disorder.
GILL, MICHAEL; CORVIN, AIDEN; MORRIS, DEREK; QUINN, EMMA (2011)A recent genome-wide association study (GWAS) reported evidence for association between rs1344706 within ZNF804A (encoding zinc-finger protein 804A) and schizophrenia (P=1.61 × 10(-7)), and stronger evidence when the ... -
Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects.
DONOHOE, GARY; MORRIS, DEREK; CORVIN, AIDEN; O'DONOGHUE, THERESE; GILL, MICHAEL; QUINN, EMMA (2009)Background: Human and animal studies have implicated the gene NOS1 in both cognition and schizophrenia susceptibility. Objectives: To investigate whether a potential schizophrenia risk SNP (rs6490121) identified in a recent ...