Browsing School of Medicine by Author "Davies, Andrew"
Now showing items 1-18 of 18
-
Challenges to delivering evidence-based palliative medicine
Davies, Andrew (2023)Established as a medical specialty in 1987, palliative medicine approaches middle age facing existential questions of identity, purpose and vision. Time has weakened strong foundations laid by Dame Cicely Saunders in ... -
Circadian rhythm disorders in patients with advanced cancer: a scoping review
Davies, Andrew (2023)Circadian rhythms can be demonstrated in several biomarkers and behavioural activities, with rhythmical patterns occurring roughly over a 24-h period. Circadian disorders occur in patients with cancer and may be associated ... -
Clinically-assisted hydration in patients in the last days of life (?CHELSEA II? trial): a cluster randomised trial
Davies, Andrew (2022)Introduction Provision of clinically assisted hydration (CAH) at the end of life is one of the most contentious issues in medicine. The aim of the ‘CHELsea II’ trial is to evaluate CAH in patients in the last days of life. ... -
Decision-making in palliative care - patient and family caregiver concordance and discordance: systematic review and narrative synthesis
Foley, Geraldine; Davies, Andrew; Mockler, David (2023)Background: Decision-making in palliative care usually involves both patients and family caregivers. However, how concordance and discordance in decision-making manifest and function between patients and family caregivers ... -
International e-Delphi consensus recommendations for the assessment and diagnosis of circadian rest-activity rhythm disorders (CARDs) in patients with cancer
Davies, Andrew (2023)Purpose: Circadian rest-Activity Rhythm Disorders (CARDs) are common in patients with cancer, particularly in advanced disease. CARDs are associated with increased symptom burden, poorer quality of life, and shorter survival. ... -
MASCC/ISOO expert opinion on the management of oral problems in patients with advanced cancer
Davies, Andrew (2022)Purpose: The Palliative Care Study Group in conjunction with the Oral Care Study Group of the Multinational Association for Supportive Care in Cancer (MASCC) formed a sub-group to develop evidence-based guidance on the ... -
Multinational Association of Supportive Care in Cancer (MASCC) expert opinion / guidance on the use of clinically-assisted hydration in patients with advanced cancer
Davies, Andrew (2024)Purpose: The provision of clinically assisted hydration (CAH) in patients with advanced cancer is controversial, and there is a paucity of specific guidance and so a diversity in clinical practice. Consequently, the ... -
Multinational Association of Supportive Care in Cancer (MASCC) expert opinion/guidance on the use of clinically assisted nutrition in patients with advanced cancer
Davies, Andrew (2022)Purpose: The pro vision of clinically assisted nutrition (CAN) in patients with advanced cancer is controversial, and there is a paucity of specific guidance, and so a diversity in clinical practice. Consequently, the ... -
Oral symptom assessment tools in patients with advanced cancer: a scoping review
Davies, Andrew (2022)Purpose: Oral symptoms are common in patients with advanced cancer. The aim of this scoping review was to identify oral symptom assessment tools that have been specifically utilised in patients with "advanced cancer". Methods: ... -
Palliative care in the era of novel oncological interventions: needs some "tweaking"
Davies, Andrew (2022)Cancer treatment has evolved enormously over the last 20 years, with developments in surgery, radiotherapy, chemo- therapy, targeted therapy, and immunotherapy. As a result, many cancer patients have improved outcomes ... -
Prognostication in advanced cancer by combining actigraphy-derived rest-activity and sleep parameters with routine clinical data: an exploratory machine learning study
Davies, Andrew (2023)Survival prediction is integral to oncology and palliative care, yet robust prognostic models remain elusive. We assessed the feasibility of combining actigraphy, sleep diary data, and routine clinical parameters to ... -
A prospective, real-world, multinational study of naloxegol for patients with cancer pain diagnosed with opioid-induced constipation - the NACASY Study
Davies, Andrew (2022)The Naloxegol Cancer Study (NACASY) was a multinational European study aimed to evaluate the 4-week safety and efficacy of naloxegol in a real-world setting in patients with cancer pain diagnosed with opioid-induced ... -
Specialist palliative for patients with cancer: more than end-of-life care
Davies, Andrew (2023)Palliative care has traditionally focused on end-of-life care for patients with advanced cancer. This has since expanded to include symptom management and quality-of-life improvement from the moment of cancer diagnosis. ... -
Supportive care: the "keystone" of modern oncology practice
Davies, Andrew (2023)The Multinational Association of Supportive Care in Cancer (MASCC) defines supportive care as "the prevention and management of the adverse effects of cancer and its treatment. This includes management of physical and ... -
Taste disturbance in patients with advanced cancer: a scoping review of clinical features and complications
Davies, Andrew (2023)Purpose: The purpose of this scoping review is to appraise the published literature on taste disturbance in patients with advanced cancer, with the specific objectives being to determine its prevalence, clinical features ... -
Validation of a French version of the Breakthrough Pain Assessment Tool in cancer patients: factorial structure, reliability and responsiveness
Davies, Andrew (2023)Objective: Breakthrough cancer pain should be properly assessed for better-personalized treatment plan. The Breakthrough Pain Assessment Tool is a 14-item tool validated in English developed for this purpose; no French ... -
Vital signs in palliative care: a scoping review
Davies, Andrew (2023)Vital signs are routinely measured in secondary healthcare settings and can be used to detect clinical problems, guide treatment, and monitor response to treatment. Vital signs are less frequently measured in palliative ... -
Xerostomia in patients with advanced cancer: a scoping review of clinical features and complications
Davies, Andrew (2023)Background: The aim of this project was to review the literature on dry mouth / xerostomia in patients with advanced cancer, with the objectives being to determine its prevalence, clinical features, and complications. Methods: ...