Browsing School of Medicine by Title
Now showing items 664-683 of 3151
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Dairy intakes in older Irish adults and effects on vitamin micronutrient status: Data from the TUDA study
(2016)Consumption of dairy products has been associated with positive health outcomes including a lower risk of hypertension, improved bone health and a reduction in the risk of type 2 diabetes. The suggested dairy intake for ... -
“Dancing with Atoms”: A tribute to Sheila Tinney
(2023)The authors present a short dynamic visualization titled “Dancing with Atoms”, produced in honor of the late Irish mathematical physicist Sheila Tinney (1918--2010), the first Irish-born and -raised woman to receive a ... -
Data linkage in medical science using the resource description framework: the AVERT model
(2018)There is an ongoing challenge as to how best manage and understand ‘big data’ in precision medicine settings. This paper describes the potential for a Linked Data approach, using a Resource Description Framework (RDF) ... -
Day care general anaesthesia for a child with bardet-biedl syndrome.
(2010)Bardet-Biedl syndrome is a very rare autosomal-recessive disorder with pan-systemic effects. The perioperative period may be hazardous for patients with this disorder. We describe the presenting features and management of ... -
Decision-making in palliative care - patient and family caregiver concordance and discordance: systematic review and narrative synthesis
(2023)Background: Decision-making in palliative care usually involves both patients and family caregivers. However, how concordance and discordance in decision-making manifest and function between patients and family caregivers ... -
Decoy receptors in the regulation of T Helper cell type 2 response
(The Rockefeller University Press, 2003) -
Decreased integrity of the fronto-temporal fibers of the left inferior occipito-frontal fasciculus associated with auditory verbal hallucinations in schizophrenia
(2016)Auditory verbal hallucinations (AVH: 'hearing voices') are found in both schizophrenia and post-traumatic stress disorder (PTSD). In this paper we first demonstrate that AVH in these two diagnoses share a qualitatively ... -
Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer
(2012)Genome instability is regarded as a hallmark of cancer. Human tumors frequently carry clonally expanded mutations in their mitochondrial DNA (mtDNA), some of which may drive cancer progression and metastasis. The high ... -
Deep Learning for Neuroimaging: Advancing Brain-Based Biomarkers of Autism Spectrum Disorder
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2023)In the last decade, deep learning (DL) has revolutionised fields like speech and vision through artificial neural networks. Can DL similarly transform biological psychiatry and neuroimaging? This thesis explores that ... -
Deep Learning Retinal Image Analysis for the Detection of CKD and Cardiovascular Risk Factors in the General Population
(2022)Background: Retinal blood vessel patterns provide an opportunity to personalize an individuals risk assessment for CKD and cardiovascular risk factors (CVRF). In this study we propose a deep learning (DL) based prediction ... -
Deep phenotyping through biomarker profiling of frontotemporal dementia (FTD) with and without co-morbid motor neuron degeneration: A multidimensional approach
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2018)PhD Thesis abstract: Trinity College Dublin Title: Deep Phenotyping Through biomarker Profiling of Frontotemporal Dementia (FTD) With and Without Co-morbid Motor Neuron Degeneration: A Multidimensional Approach Authors: ... -
Defiency of natural killer receptor expressing cells in haemophagocytic lymphohistiocytosis
(Trinity College (Dublin, Ireland). Department of Immunology, 2002)Two children, patient A and patient B, were diagnosed on clinical and histological grounds to have haemophagocytic lymphohistiocytosis (HLH) (Henter et al. 1991a; Arico et al. 2001a). Clinical presentation of HLH consists ... -
Defining a successful esophagectomy.
(2014) -
Defining inherited haematological disease within the Irish traveller population
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Haematology, 2006)The Traveller Community in Ireland constitutes a minority of nomadic or semi-nomadic people, sharing a common Irish ancestry. The Traveller Health Study showed that in 1987, Travellers were only reaching the life expectancy ... -
Defining the mechanism of protection of the class 1 Allele HLA-A *03 in a single source outbreak of Hepatitis C Virus
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2011)Hepatitis C virus infects approximately 180 million persons worldwide and results in serious liver disease. Significant obstacles have hindered efforts to design an effective vaccine; in particular these include the profound ... -
Defining the mechanisms through which von willebrand factor sialic acid expression regulates in vivo clearance
(Trinity College Dublin. School of Medicine. Discipline of Haematology, 2019)Von Willebrand Factor (VWF) is a complex plasma sialoglycoprotein which plays a key role in maintaining normal haemostasis. While the biosynthesis, structure, and functions of VWF are well characterised, the molecular ... -
Defining the role of RORα in the functionality of distinct immune cell populations
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2021)The transcription factor Retinoic acid-related Orphan Receptor (ROR)-a has roles in metabolism, circadian rhythm and cellular development, such as Th17 cells and group 2 innate lymphoid cells (ILC2). The identification ...