Browsing Clinical Microbiology by Author "ROGERS, THOMAS"
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Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in New Zealand
O'TOOLE, RONAN; ROGERS, THOMAS (2014)Extensively drug-resistant (XDR) tuberculosis has now been described in >90 countries worldwide. The first case of XDR tuberculosis (XDR-TB) in New Zealand was recorded in 2010. We report the draft whole-genome sequence ... -
Gene expression profiles of human dendritic cells interacting with Aspergillus fumigatus in a bilayer model of the alveolar epithelium/endothelium interface.
ROGERS, THOMAS (2014)The initial stages of the interaction between the host and Aspergillus fumigatus at the alveolar surface of the human lung are critical in the establishment of aspergillosis. Using an in vitro bilayer model of the alveolus, ... -
Identification of a novel mutation at the primary dimer interface of GyrA conferring fluoroquinolone resistance in Clostridium difficile
MAC AOG?IN, MICHE?L; MOLONEY, GERALDINE; ROGERS, THOMAS (2015)The aim of this study was to determine whether alternative resistance mechanisms, other than mutation in the quinolone resistance-determining region (QRDR) of DNA gyrase, could confer fluoroquin ... -
Response of Extraintestinal Pathogenic Escherichia coli to Human Serum Reveals a Protective Role for Rcs-Regulated Exopolysaccharide Colanic Acid.
SMITH, STEPHEN; MORAN, GARY; ROGERS, THOMAS (2014)Extraintestinal Escherichia coli (ExPEC) organisms are the leading cause of Gram-negative bacterial bloodstream infections. These bacteria adapt to survival in the bloodstream through expression of factors involved in ... -
Staphylococcus aureus Colonization: Modulation of Host Immune Response and Impact on Human Vaccine Design.
MCLOUGHLIN, RACHEL; ROGERS, THOMAS (2014)In apparent contrast to its invasive potential Staphylococcus aureus colonizes the anterior nares of 20-80% of the human population. The relationship between host and microbe appears particularly individualized and ...