Browsing Chemistry by Author "Hanafin, Una"

Now showing items 1-1 of 1

    • Synthesis of some 8-Aza-7-deazaguanines as potential inactivators of Atase 

      Hanafin, Una (Trinity College (Dublin, Ireland). School of Chemistry, 2004)
      Certain cancer chemotherapeutic agents act by alkylating the O6-position of guanine residues in DNA. This lesion can ultimately cause the death of the targeted cancer cells. However, the efficacy of the cytotoxic effect ...