Browsing Chemistry by Date of Publication
Now showing items 21-40 of 1269
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Nitrile and non-nitrile pyridine products from the reaction of 2-cyano- 3-(x-nitrophenyl)prop-2-enamides with methyl 3-oxobutanoate
(1999)The reaction of 2-cyano-3-(x-nitrophenyl)prop-2-enamides with methyl 3-oxobutanoate affords methyl 4-aryl-3-cyano-6-methyl-2-oxo-1,2-dihydropyridine-5-carboxylates, methyl 4-aryl-5-cyano-2-hydroxy-2-methyl-6-oxopiperidin ... -
Substituted 3,4-pyridynes: clean cycloadditions
(Royal Society of Chemistry, 2000)The stabilisation of 3,4-pyridyne (1) by an alkoxy group adjacent to the ring nitrogen is reported. The regioselective lithiation of 2-ethoxy- (14), 2-methoxy- (18), 2-isopropoxy- (19) and 6-isopropoxy- (26) -3-chloropyridines ... -
Benzylic Oligothioethers as Ditopic Ligands for Group 6 Transition Metal Carbonyls
(2000)The co-ordination preferences of a family of novel thioethers based on (alkylsulfanylmethyl)benzene were examined. The alkyl chain length and the number and position of the thioether substituents were varied. The ligands ... -
Palladium bis(phosphinite) 'PCP'-pincer complexes and their application as catalysts in the Suzuki Reaction
(2000)Palladium complexes of inexpensive, easily synthesised bis(phosphinite) `PCP ?-pincer ligands show good activity in the Suzuki coupling of deactivated and sterically hindered aryl bromides -
The synthesis and testing of inhibitors for the enzyme GTP-cyclohydrolase (I)
(Trinity College (Dublin, Ireland). School of Chemistry, 2000)This thesis investigates the design and synthesis of compounds to be tested as inhibitors of the enzyme guanosine triphosphate cyclohydrolase (I), an enzyme which plays an important role in the biosynthesis of almost all ... -
Bioremediation of unresolved complex mixtures in marine oil spills : an analytical perspective
(Trinity College (Dublin, Ireland). School of Chemistry, 2000)Unresolved complex mixture (UCM) is the fraction of some petroleums that cannot be resolved by conventional gas chromatography and is characteristic of biodegraded petroleum oils and some refined products such as lubricating ... -
The synthesis of steroidal-based anion receptors and analysis of their binding properties
(Trinity College (Dublin, Ireland). School of Chemistry, 2000)Chapter one is an introduction to molecular recognition and supramolecular chemistry; their origin and the history of their progress in recent years. It includes a brief account of the factors that must be considered when ... -
Towards a comprehensive system for the recognition of double helical DNA : components for T and A
(Trinity College (Dublin, Ireland). School of Chemistry, 2000)This thesis gives an account of the attempted synthesis of sequence selective double stranded DNA ligands. Two distinctive ligands types were envisaged, a pyrrolo[2', 3': 4, 5] thieno [2, 3-d]imidazole system (1.40 and ... -
The immobilisation of TiO2 in various heterogeneous hosts for the photocatalytic oxidation of cyanide
(Trinity College (Dublin, Ireland). School of Chemistry, 2000)The main focus of this study lies in the preparation and characterisation of TiO2. The formation of a nanoparticulate semiconductor may offer interesting photophysical properties and have applications as a photocatalyst. ... -
Mathematical modelling of diffusion in physico-chemical systems
(Trinity College (Dublin, Ireland). School of Chemistry, 2000)The purpose of this thesis was to investigate the usefulness of mathematical modelling as an aid to understanding the physico chemical processes of iontophoresis in transdermal drug delivery and electrochemical sensor ... -
Anionic polymerisation photoinitiated by ruthenium polypyridyl complexes
(Trinity College (Dublin, Ireland). School of Chemistry, 2000)A new group of photoinitiators of ethylcyanoacrylate monomers based on ruthenium polypyridyl complexes has been investigated. The photoinitiators, of general formula [Ru(DMB)2(L)2]2+, where L = 4-picoline, 2-picoline, ... -
Synthesis and reactions of new pyrimidines containing functionalised side chains
(Trinity College (Dublin, Ireland). School of Chemistry, 2000)Thin layer chromatography was carried out using Merck Kiesgel 60 F254 0.2 mm silica gel plates. Visualisation was by means of ultra violet light at 254 nm or by development in potassium permanganate solution. Flash ... -
Explorations in solvaton models of solvation within a quantum chemical framework
(Trinity College (Dublin, Ireland). School of Chemistry, 2000)The purpose of this thesis is to investigate the potential of developing a tractable model for solvation of large systems within a quantum chemical framework. Candidate computational methods are reviewed ranging from ab ... -
The origin of the electron distribution in SnO
(2001)The origin of the electron distribution in SnO Graeme W. Watson Department of Chemistry, Trinity College, Dublin 2, Ireland ~ Received 12 September 2000; accepted 17 October 2000 ! Gradient corrected density functional ... -
Theoretical study of the valence and core photoemission spectra of C-60
(2001)The photoionization cross section and angular distribution relative to all primary ionizations in C60 have been computed employing a convergent one-centre expansion and an LDA hamiltonian over an extended energy range. The ... -
The adsorption of simple amines on platinum surfaces
(Trinity College (Dublin, Ireland). School of Chemistry, 2001)This thesis presents the results of an investigation of the adsorption of methylamine, dimethylamine, trimethylamine and ethylenediamine on Pt(111) and Pt(331). The chemical composition and geometric structure of the clean ... -
Ferrocenylalkynes as ligands in transition metal complexes
(2001)Several ferrocenylalkynes have been prepared and their reaction with dicobalt octacarbonyl led to the formation of [Co2(CO)6(?-?2 ? ?2-ethynylferrocene)] 1, [Co2(CO)6(?-?2 ? ?2-1,4-bis(ferrocenyl)butadiyne)] 2, [(Co2(CO)6)2(?-?2 ... -
Chiral hypernucleophilic acylation catalysts and synthesis of bipyridyls via palladium-catalysed reductive homocoupling of chloropyridines
(Trinity College (Dublin, Ireland). School of Chemistry, 2001)Chapter 1 of this thesis discusses the explosion of interest in the non-enzymatic kinetic resolution of secondary alcohols catalysed by chiral derivatives of the hypemucleophilic acylation catalyst, 4-dimethylaminopyridine. ... -
A study of anionic drug transport processes governing passive and enhanced transdermal delivery
(Trinity College (Dublin, Ireland). School of Chemistry, 2001)The research contained herein is directed at defining some of the factors which govern the passive and enhanced transdermal transport of anionic drugs and will extend current knowledge which largely pertains to the analogous ... -
Preparation of uniform ZnO microparticles by hydrothermal methods; Conventional vs. microwave heating
(Trinity College (Dublin, Ireland). School of Chemistry, 2001)Uniform particles of ZnO and Zn(OH)2 have been prepared in the micron size range, using a number of hydrothermal methods. In a forced hydrolysis procedure, when aqueous zinc nitrate solutions are reacted with sodium ...