Browsing Pharmacy and Pharmaceutical Sciences (Scholarly Publications) by Author "Walsh, John"
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HPLC profiling of Mimosa pudica polyphenols and their non-invasive biophysical investigations for anti-dermatoheliotic and skin reinstating potential
Walsh, John (2019)Plant-derived polyphenols are known to have promising biological activities including antioxidant and anti-tyrosinase and may be a potential candidate for anti-dermatoheliotic remedy. The present study was performedto ... -
Part Two: Evaluation of N-methylbupropion as a Potential Bupropion Prodrug
Walsh, John (2014)N-methylbupropion was selected as a potential prodrug from our in vitro screening of analogues of bupropion described in the preceding paper. This study describes in vivo pharmacokinetics of N-methylbupropion in the ... -
Synthesis, screening and pharmacokinetic evaluation of potential prodrugs of bupropion
Walsh, John (2014)In general, prodrugs are developed to circumvent deficiencies associated with the absorption, distribution, metabolism, excretion or toxicological (ADMET) profile associated with the active drug. In our study, we select ...