Browsing Pharmacy and Pharmaceutical Sciences (Scholarly Publications) by Author "TAJBER, LIDIA"
Now showing items 1-20 of 39
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Amorphous polymeric drug salts as ionic solid dispersion forms of ciprofloxacin
TAJBER, LIDIA (2017) -
Bulk, surface properties and water uptake mechanisms of salt/acid amorphous composite systems
TAJBER, LIDIA; HEALY, ANNE (2013)Developing amorphous pharmaceuticals can be desirable due to advantageous biopharmaceutical properties. Low glass transition temperature (Tg) amorphous drugs can be protected from crystallisation by mixing with high Tg ... -
Characterisation, solubility and intrinsic dissolution behaviour of benzamide:dibenzyl sulfoxide cocrystal
HEALY, ANNE; CORRIGAN, OWEN; TAJBER, LIDIA; GROSSJOHANN, CHRISTINE (2012)This study examined the 1:1 cocrystal benzamide:dibenzyl sulfoxide, comprising the poorly water soluble dibenzyl sulfoxide (DBSO) and the more soluble benzamide (BA), to establish if this cocrystal shows advantages in terms ... -
Chondroitin-based nanoplexes as peptide delivery systems--Investigations into the self-assembly process, solid-state and extended release characteristics.
TAJBER, LIDIA; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS (2015) -
Co-spray dried carbohydrate microparticles: crystallisation delay/inhibition and improved aerosolization characteristics through the incorporation of hydroxypropyl-?-cyclodextrin with amorphous raffinose or trehalose
TAJBER, LIDIA; HEALY, ANNE (2015)PURPOSE: To formulate and investigate the physicochemical properties, physical stability and aerosolization characteristics of nanoporous/nanoparticulate microparticles (NPMPs) prepared by co-spray drying the sugars ... -
Comparative study of different methods for the prediction of drug-polymer solubility
TAJBER, LIDIA; HEALY, ANNE (2015) -
Dry powders for oral inhalation free of lactose carrier particles
TAJBER, LIDIA; HEALY, ANNE (2014)Dry powder inhaler (DPI) products have traditionally comprised a simple formulation of micronised drug mixed with a carrier excipient, typically lactose monohydrate. The presence of the carrier is aimed at overcoming issues ... -
Exploring the assembly process and properties of novel crosslinker-free hyaluronate-based polyelectrolyte complex nanocarriers
TAJBER, LIDIA; SANTOS-MARTINEZ, MARIA; CORRIGAN, OWEN; UMERSKA, ANITA MONIKA; PALUCH, KRZYSZTOF; MEDINA MARTIN, CARLOS (2012) -
Formation and physicochemical properties of crystalline and amorphous salts with different stoichiometries formed between ciprofloxacin and succinic acid
TAJBER, LIDIA; HEALY, ANNE (2013)Multi-ionisable compounds, such as dicarboxylic acids, offer the possibility of forming salts of drugs with multiple stoichiometries. Attempts to crystallise ciprofloxacin, a poorly water soluble, amphoteric ... -
Heat induced evaporative antisolvent nanoprecipitation (HIEAN) of itraconazole.
TAJBER, LIDIA (2014)traconazole (ITR) is an antifungal drug with a limited bioavailability due to its poor aqueous solubility. In this study, ITR was used to investigate the impact of nanonisation and solid state change on drug's apparent ... -
Impact of process variables on the micromeritic and physicochemical properties of spray dried microparticles - Part II. Physicochemical characterisation of spray dried materials
HEALY, ANNE; AMARO, MARIA INES; TAJBER, LIDIA; PALUCH, KRZYSZTOF; CORRIGAN, OWEN (2012) -
Impact of process variables on the micromeritic and physicochemical properties of spray dried porous microparticles - Part I. Introduction of a new Morphology Classification System
HEALY, ANNE; TAJBER, LIDIA; CORRIGAN, OWEN; PALUCH, KRZYSZTOF (2012) -
Intermolecular interactions between salmon calcitonin, hyaluronate, and chitosan and their impact on the process of formation and properties of peptide-loaded nanoparticles.
CORRIGAN, OWEN; TAJBER, LIDIA (2014)The principal aim of this work was to study the formulation of a ternary complex comprising salmon calcitonin (sCT), hyaluronate (HA), and chitosan (CS) in a nanoparticle (NP) format. As interactions between the constituents ... -
Molecular dynamics and physical stability of coamorphous ezetimib and indapamide mixtures
TAJBER, LIDIA (2015) -
Nanostructured systems containing babassu (Orbignya speciosa) oil as a potential alternative therapy for benign prostatic hyperplasia.
TAJBER, LIDIA (2013)The oil of babassu tree nuts (Orbignya speciosa) is a potential alternative for treatment and prophylaxis of benign prostatic hyperplasia. Improved results can be obtained by drug vectorization to the hyperplastic tissue. ...