Browsing Pharmacy and Pharmaceutical Sciences (Scholarly Publications) by Author "Sheridan, Helen"
Now showing items 1-6 of 6
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Bioactive Indanes: Development and validation of an LC-MS/MS bioanalytical method for the determination of PH46A, a new potential anti-inflammatory agent, in dog and rat plasma and its application to a pharmacokinetic study in dog.
Sheridan, Helen; Scalabrino, Gaia A.; Zhang, Tao; Frankish, Neil (2020)A new chemical entity, which is a chiral indane dimer, PH46A, has been developed by our research group. As a clinical candidate. PH46A has recently completed Phase I clinical studies in man. Previously, during its pre-clinical ... -
Carissa spinarum L.: A Case Study in Ethnobotany and Bioprospecting Research
Sheridan, Helen; Smyth, Ciara (Intech Open, 2022)This study explores ethnobiological and bioprospecting research through the lens of Carissa spinarum L., using it as a case study to examine wider trends in such research. Hunn’s Phasing in Ethnobiology is used as a ... -
Effect of Extraction Methods on Essential Oil Composition: A Case Study of Irish Bog Myrtle -Myrica gale L.
Sheridan, Helen; Nagar, Shipra (2023)Myrica gale is an aromatic peatland shrub that has reported traditional use as an insect repellent. Different extraction methodologies were used in this study to isolate the essential oil of Myrica gale L., including ... -
The indane diastereoisomers, PH2 and PH5: divergence between their effects in delayed-type hypersensitivity models and a model of colitis
Sheridan, Helen; Frankish, Neil (2018) -
Traditional Chinese Medicine: From Aqueous Extracts to Therapeutic Formulae
Sheridan, Helen (IntechOpen, 2019)Traditional Chinese medicine (TCM) is one of the most established systems of medicine in the world. The therapeutic formulae used in TCM are frequently derived from aqueous decoctions of single plants or complex multicomponent ...