Browsing Pharmacy and Pharmaceutical Sciences (Scholarly Publications) by Author "Mantalaris, Athanasios"
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Dynamic human erythropoiesis in a three-dimensional perfusion bone marrow biomimicry
Mantalaris, Athanasios; Panoskaltsis, Nicki (2019)Traditional culture systems for human erythropoiesis lack microenvironmental niches, spatial marrow gradients and dense cellularity rendering them incapable of effectively translating marrow physiology ex vivo. Herein, a ... -
Long-term cytokine-free expansion of cord blood mononuclear cells in three-dimensional scaffolds
Panoskaltsis, Nicki; Mantalaris, Athanasios (2011)Cord blood expansion ex vivo can be achieved in liquid suspension through the addition of cytokines at the expense of often undesirable cell differentiation. In order to derive a cytokine-free dynamic culture system, we ...