Browsing Pharmacy and Pharmaceutical Sciences (Scholarly Publications) by Title
Now showing items 201-220 of 445
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Inhibiting extracellular vesicles formation and release: a review of EV inhibitors.
(2019)It is now becoming well established that vesicles are released from a broad range of cell types and are involved in cell-to-cell communication, both in physiological and pathological conditions. Once outside the cell, these ... -
Intermolecular interactions between salmon calcitonin, hyaluronate, and chitosan and their impact on the process of formation and properties of peptide-loaded nanoparticles.
(2014)The principal aim of this work was to study the formulation of a ternary complex comprising salmon calcitonin (sCT), hyaluronate (HA), and chitosan (CS) in a nanoparticle (NP) format. As interactions between the constituents ... -
Interprofessional Education focused on Medication Safety: A Systematic Review.
(2022)Safe medication use necessitates interprofessional working, with calls to enhance interprofessional education (IPE) focusing on medication safety (MS) in healthcare professional (HCP) curricula. Little is known about the ... -
The interrelation of Physicochemical Parameters and Topological Descriptors for a series of O-blocking Agents
(American Chemical Society, 2002)The intercorrelation between a series of physicochemical parameters and topological indices for a set of a-blockers is investigated. Partition coefficients are calculated using the ClogP program, and the results are compared ... -
Interventions for improving medication reconciliation across transitions of care (Protocol)
(John Wiley & Sons, 2013-10-30)This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effect of medication reconciliation on medication discrepancies, patient related outcomes and healthcare utilisation ... -
Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation
(2018)Polyelectrolyte nanoparticle constructs (NPs) comprising salmon calcitonin (sCT), chitosan (CS), and hyaluronic acid (HA) were previously established as having anti-inflammatory potential when injected via the intra-articular ... -
Investigating the effect of solubility and density gradients on local hydrodynamics and drug dissolution in the USP 4 dissolution apparatus
(2011)The aim of this investigation was to evaluate the effect of solubility and related solution density gradients, on hydrodynamics and dissolution rate in a low velocity pulsing flow, in the USP 4 flow-through dissolution ... -
Investigation of MRP-1 protein and MDR-1 P-glycoprotein expression in invasive breast cancer: a prognostic study
(2004)The efficacy of breast cancer treatment is limited by the development of resistance to various chemotherapeutic agents. We conducted a retrospective study of the expression of 2 drug resistance efflux pumps, MRP‐1 and MDR‐1 ... -
ISEV position paper: extracellular vesicle RNA analysis and bioinformatics.
(2013)Extracellular vesicles (EVs) are the collective term for the various vesicles that are released by cells into the extracellular space. Such vesicles include exosomes and microvesicles, which vary by their size and/or protein ... -
Isosorbide-based cholinesterase inhibitors; replacement of 5-ester groups leading to increased stability
(2010)Isosorbide-2-carbamate-5-esters are highly potent and selective butyrylcholinesterase inhibitors with potential utility in the treatment of Alzheimer?s Disease (AD). They are stable in human plasma but in mouse plasma they ... -
Isosteviol has beneficial effects on palmitate-induced cell dysfunction and gene expression.
(2012)BACKGROUND: Long-term exposure to high levels of fatty acids impairs insulin secretion and exaggerates glucagon secretion. The aim of this study was to explore if the antihyperglycemic agent, Isosteviol (ISV), is able ...