School of Dental Sciences: Recent submissions
Now showing items 1-5 of 257
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Oral leukoplakia - an investigation of its microbiome and of the association of clinical and microbial features with the degree of dysplasia
Background: With growing evidence of a shift in the oral microbiome associated with oral squamous cell carcinoma, it was hypothesised that the microbiome of oral leukoplakia (OLK), the most common of the 11 recognised oral ... -
The Oro-Nasal Cavity as an Endogenous Staphylococcal Reservoir for Diabetic Foot Ulcer Infections Investigated by Whole Genome-Sequencing and Disinfection of Debrided Foot Ulcer Tissues using Electrochemically-Activated Hypochlorous Acid Solution
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)Background and study purpose Type II diabetes mellitus is highly prevalent worldwide (approximately 6.3-10.5% of the global population), and in the population of the Republic of Ireland (9.5%), and continues to increase ... -
An investigation into molecular biomarkers of pulp inflammation and cell death and their potential use as a diagnostic tool.
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)The overarching aim of the thesis was to present a robust method of collecting and analysing pulpal blood, to inform quality biomarker discovery with the potential to detect the `threshold? between teeth amenable to vital ... -
An investigation of the hydraulic calcium silicate cement, Biodentine, as a vital pulp treatment material
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)A recent upsurge in the popularity of Vital Pulp Treatment (VPT) has been attributed to a deeper understanding of the pulp reparative processes, biomaterial development and technological advancement. The introduction of ... -
The multi-faceted effects of ethanol exposure on oral dysplastic and cancer cells.
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)Oral cancers (OC) are cancers that arise in several regions within the oral cavity such as the lips, gums, tongue, lining of the cheeks, and the floor or roof of the mouth. Approximately 400,000 cases were diagnosed worldwide ...