Browsing School of Dental Sciences by Title
Now showing items 53-72 of 104
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IDENTIFICATION AND CHARACTERIZATION OF THE MULTIDRUG RESISTANCE GENE cfr IN PANTON-VALENTINE LEUKOCIDIN-POSITIVE ST8-METHICILLIN-RESISTANT Staphylococcus aureus-IVa (USA300)
(2010)The staphylococcal cfr gene mediates resistance to phenicols, lincosamides, oxazolidinones, pleuromutilins, and streptogramin A, a phenotype that has been termed PhLOPSA. The cfr gene has mainly been associated with ... -
An in-vitro assessment of the retrievability of fractured dental implant abutment screws
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2021)Background: Fractured abutment screws have the potential to preclude restoration of osseointegrated dental implants and as a result, a wide range of products and techniques aimed at retrieving fractured screw fragments ... -
An Investigation into Player Compliance and Level of Protection Afforded by Mouthguards worn by Children Playing Sport in Ireland
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2020)Background: Dental trauma is a significant global public health issue, affecting 1 billion people worldwide. Up to 40% of dental injuries are sports related and preventable through the use of mouthguards. In Ireland, the ... -
Investigation into the molecular mechanisms of itraconazole resistance in Candida dubliniensis
(Trinity College (Dublin, Ireland). School of Dental Science, 2003)Candida dubliniensis is a recently identified yeast species primarily associated with oral carriage and infection in HIV-infected individuals. Previous studies have shown that only a small number of clinical isolates are ... -
Investigation of novel methods to facilitate dental implant osseointegration in areas of deficient bone and in areas of recent tooth extraction
(Trinity College (Dublin, Ireland). School of Dental Science, 2013)The aim of this this series of studies was to identify methods to prevent alveolar ridge resorption following tooth extractions and also to invesigate conservative methods of providing anchorage in areas of deficient bone ... -
An investigation of the hydraulic calcium silicate cement, Biodentine, as a vital pulp treatment material
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)A recent upsurge in the popularity of Vital Pulp Treatment (VPT) has been attributed to a deeper understanding of the pulp reparative processes, biomaterial development and technological advancement. The introduction of ... -
Investigation of the microbiological profile of oral leukoplakia
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2019)Oral leukoplakia (OLK) presents as a white patch on the oral mucosa and is recognised as a potentially malignant lesion. Although colonisation of these patches with yeast such as Candida albicans has been reported, little ... -
An Investigation of the Prevalence, Population Structure and Relatedness of Environmental, Healthcare Worker and Patient Staphylococcus aureus Isolates Recovered from Multi-bed Patient Rooms in an Irish Teaching hospital by Whole-Genome Sequencing
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2020)The putative role of the air in Staphylococcus aureus transmission in multi-bed ward areas of hospitals, where the majority of in-patients are cared for, has not yet been elucidated. The work described in this thesis ... -
Investigations into the development, diagnosis and treatment of oral cancer
(Trinity College (Dublin, Ireland). School of Dental Science, 2015)Oral cancer is the sixth most common cancer in the world and has one of the highest mortality rates primarily due to the disease being largely asymptomatic until the latter stages. It is among one of the major worldwide ... -
Is it worth using low-cost glass ionomer cements for occlusal ART restorations in primary molars? 2-year survival and cost analysis of a Randomized clinical trial
(2020)Objective: To evaluate the 2-year survival rate and the cost-effectiveness of Atraumatic Restorative Treatment (ART) using three different glass ionomer cements (GICs) for restoring occlusal dentin caries lesions in primary ... -
Medication related osteonecrosis of the jaws: Prospective cohort study analysing the aetiology, microbiology, and response to surgical debridement with adjunctive leucocyte and platelet rich fibrin (L-PRF)
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2018)Background Bisphosphonates and RANK ligand inhibitors are antiresorptive medications which are prescribed for the treatment of osteoporosis and bone metastases. These medications inhibit osteoclastic action thereby ... -
METICILLIN-RSISTANT Staphylococcus aureus TRANSMISSION AMONG HEALTHCARE WORKERS, PATIENTS AND THE ENVIRONMENT IN A LARGE ACUTE HOSPITAL UNDER NON-OUTBREAK CONDITIONS INVESTIGATED BY WHOLE-GENOME SEQUENCING
(2021)Background: The role of meticillin-resistant Staphylococcus aureus (MRSA) colonization of healthcare workers (HCWs), patients and the hospital environment in MRSA transmission in non-outbreak settings is poorly understood. Aims: ... -
Meticillin-susceptible Staphylococcus aureus transmission among healthcare workers, patients and the environment in a large acute hospital under non-outbreak conditions investigated using whole-genome sequencing
(2022)Background: The role of meticillin-susceptible Staphylococcus aureus (MSSA) colonization of healthcare workers (HCWs), patients and the hospital environment in MSSA transmission events (TEs) is poorly understood. Aims: ... -
microRNA, Dental Pulp Cell Mineralisation and Therapeutic Epigenetic Modification
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2022)Current clinical approaches to the management of deep caries and symptomatic pulpitis are destructive and costly, generally involving removal of the entire pulp as part of a root canal treatment (RCT) procedure. Contemporary ... -
Minimisation of Microbial Reservoirs and Infection Risks From Washbasin U-bend Traps Using a Novel Automated Disinfection System with Electrochemically Activated Solutions
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2017)Background: Washbasin and sink U-bends are ubiquitous in virtually all buildings including hospitals and smaller healthcare premises. They have been used for over a century and their principal purpose is to prevent foul ... -
MOLECULAR EPIDEMIOLOGY. PHYLOGENY AND EVOLUTION OF Candida albicans
(2014)A small number of Candida species form part of the normal microbial flora of mucosal surfaces in humans and may give rise to opportunistic infections when host defences are impaired. Candida albicans is by far the most ...