Browsing School of Dental Sciences by Title
Now showing items 30-49 of 257
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CANDIDA ALBICANS VERSUS CANDIDA DUBLINIENSIS: WHY IS C. ALBICANS MORE PATHOGENIC?
(2012)Candida albicans and Candida dubliniensis are highly related pathogenic yeast species. However, C. albicans is far more prevalent in human infection and has been shown to be more pathogenic in a wide range of infection ... -
The Candida albicans-Specific Gene EED1 Encodes a Key Regulator of Hyphal Extension
(2011)The extension of germ tubes into elongated hyphae by Candida albicans is essential for damage of host cells. The C. albicans-specific gene EED1 plays a crucial role in this extension and maintenance of filamentous growth. ... -
Candida dubliniensis: An update
(1999)The increased incidence of fungal infections during the last decade has been well-documented. Given that one of the most important factors contributing to this phenomenon is the increased numbers of immunocompromised ... -
Characterisation of Candida albicans populations associated with chronic hyperplastic candidosis (Candida leukoplakia) and non-Candida leukoplakia lesions in patients presenting with oral leukoplakic lesions in Ireland
(Trinity College (Dublin, Ireland). School of Dental Science, 2011)Oral squamous cell carcinoma is a significant global health problem, affecting about a half of a million people worldwide annually. Oral leukoplakic lesions have been reported to have significantly increased potential for ... -
Characterisation of Staphylococcal and Candida Populations from Healthy and Diseased Oral and Subgingival Sites Reveals a High Prevalence and Diversity of the Arginine Catabolic Mobile Element ACME in Staphylococcus epidermidis
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2018)The oral cavity harbours a diverse microbiological population, that exists mainly as plaque biofilm, the accumulation of which is associated with oral diseases such as periodontal disease and peri-implantitis. Traditionally, ... -
CHARACTERIZATION OF A NOVEL ARGININE CATABOLIC MOBILE ELEMENT (ACME) AND STAPHYLOCOCCAL CHROMOSOMAL CASSETTE mec COMPOSITE ISLAND WITH SIGNIFICANT HOMOLOGY TO STAPHYLOCOCCUS EPIDERMIDIS ACME TYPE II IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS GENOTYPE ST22-MRSA-IV
(2011)The arginine catabolic mobile element (ACME) is prevalent among ST8-MRSA-IVa (USA300) isolates and evidence suggests that ACME enhances the ability of ST8-MRSA-IVa to grow and survive on its host. ACME has been identified ... -
A clinical and biochemical investigation on the effects of non-surgical periodontal treatment of chronic and aggressive periodontitis. A comparative study.
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2018)Although Chronic (CP) and Aggressive Periodontitis (GAP) were classified in the 1999 world workshop and specific defining characteristics have been identified in this classification, clinically it is difficult to differentiate ... -
Clinical experience of undergraduate dental students in paediatric dentistry: A 5-year cross-sectional study
(2022)Introduction: The clinical experience of undergraduate dental students in Paediatric Dentistry has a profound influence on their future confidence. The purpose of this study was to evaluate the clinical experience of ... -
Collagen-glycosaminoglycan scaffold and mesenchymal stem cells for bone tissue engineering
(Trinity College (Dublin, Ireland). School of Dental Science, 2009)Tissue engineering using cell-seeded biodegradable scaffolds offers a new bone regenerative approach that might circumvent many of the limitations of current therapeutic modalities. This thesis reports on a number of in ... -
COMPARATIVE ADHERENCE OF CANDIDA ALBICANS AND CANDIDA DUBLINIENSIS TO HUMAN BUCCAL EPITHELIAL CELLS AND EXTRACELLULAR MATRIX PROTEINS
(2014)Candida albicans and Candida dubliniensis are very closely related pathogenic yeast species. Despite their close relationship, the former is a far more successful coloniser and pathogen of humans. The purpose of the current ... -
Comparative analysis of stress responses in C. albicans and C. dubliniensis
(Trinity College (Dublin, Ireland). School of Dental Science, 2006)Candida dubliniensis is apathogenic yeast that was first identified as a novel species in 1995. It is phylogenetically very closely related to C. albicans. However, despite the close relationship between the two species, ... -
Comparative analysis of the filamentous growth regulators EED1 in Candida albicans and MDP1 in Candida dubliniensis
(Trinity College (Dublin, Ireland). School of Dental Science, 2009)Candida albicans, the major fungal pathogen in humans is closely related to Candida dubliniensis. C. dubliniensis is less virulent than C. albicans in all models of infection. Comparative analysis of the C. albicans and ... -
Comparative genetic analysis of nosocomial methicillin-resistant Staphylococcus aureus populations in Ireland 1971-2004
(Trinity College (Dublin, Ireland). School of Dental Science, 2005)Methicillin-resistant Staphylococcus aureus (MRSA) is the most prevalent pathogen responsible for nosocomial infections worldwide and Ireland has one of the highest rates of nosocomial MRSA infections in Europe. In the ... -
COMPARATIVE GENOMICS AND THE EVOLUTION OF PATHOGENICITY IN HUMAN PATHOGENIC FUNGI
(2011)Because most fungi have evolved to be free-living in the environment and because the infections they cause are usually opportunistic in nature, it is often difficult to identify specific traits that contribute to fungal ... -
COMPARATIVE GENOMICS USING CANDIDA ALBICANS DNA MICROARRAYS REVEALS ABSENCE AND DIVERGENCE OF VIRULENCE ASSOCIATED GENES IN CANDIDA DUBLINIENSIS
(2004)Candida dubliniensis is a pathogenic yeast species closely related to Candida albicans. However, it is less frequently associated with human disease and displays reduced virulence in animal models of infection. We have ... -
Comparative growth analysis of Candida dubliniensis and Candida albicans in vitro and in selected infection models
(Trinity College (Dublin, Ireland). School of Dental Science, 2006)Candida dubliniensis is the species most closely related to C. albicans and is primarily associated with colonisation and oral candidiasis in Human Immunodeficiency Virus (HlV)-infected individuals and AIDS patients. Despite ... -
A comparative study of the effect of one-suture and suture-less techniques on post-operative complications following third molar surgery
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2017)Title: A comparative study of the effect of one-suture and suture-less techniques on post-operative complications following third molar surgery. Author: Dr Saleh Alkadi BDS(Hons), MFDS RCSI, NBDE Objective: Lower third ... -
COMPARATIVE TRANSCRIPT PROFILING OF Candida albicans AND Candida dubliniensis IDENTIFIES SFL2, A C. albicans GENE REQUIRED FOR VIRULENCE IN A RECONSTITUTED EPITHELIAL INFECTION MODEL
(2010)Candida albicans and Candida dubliniensis are closely related species displaying differences in virulence and genome content, therefore providing potential opportunities to identify novel C. albicans virulence genes. C. ...