School of Chemistry: Recent submissions
Now showing items 1-5 of 1269
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Nucleoside and Oligonucleotide Modification for Targeting the DNA Damage Repair Enzyme SNM1A
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The exonuclease SNM1A is a key enzyme involved in the repair of interstrand crosslinks, a highly cytotoxic form of DNA damage. As cells depleted in this enzyme display increased sensitivity to chemotherapeutic agents such ... -
Exploring new techniques for the surface modification of high-performance polymer materials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The surface modification of high-performance polymers is a critical area of research, as these materials possess excellent mechanical, chemical, and thermal properties but often lack the surface functionality required for ... -
Novel Chemical Modalities and Methods for Protein Profiling
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The activity of proteins is pivotal to the chemistry of cells. In order to deconvolute the complexity of living systems, chemical tools can be used to study active proteins under different cellular states. Amongst these ... -
Tailored nitrogen-containing polyaromatics - from surfaces to stacks
(Trinity College (Dublin, Ireland). School of Chemistry, 2016)Chapter 1: This chapter gives a broad introduction to the subjects of graphene and nanographenes, which are discussed in subsequent chapters. Common methodologies for the synthesis of substituted polyphenylenes and ... -
Development of a solution-based process for hydroxyapatite and functionalised hydroxyapatite
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)Hydroxyapatite coatings have long been established as a means of improving the osteointegration of metallic orthopaedic implants. Nonetheless there are both technical and commercial drawbacks associated with industrial ...