Recent Submissions

  • HPV Primary Screening Pilot Study: molecular testing of potential triage strategies for HPV-positive women. 

    REYNOLDS, STEPHEN HUGH (Trinity College Dublin. School of Medicine. Discipline of Histopathology, 2020)
    Cytological based screening programmes are being phased out in favour of HPV-based screening both in Ireland and internationally. Infection with HPV is the primary aetiological agent in the development of cervical cancer. ...
  • The role of MyD88 in embryonal carcinoma stem cells 

    Sulaiman, Gomaa M. A. (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2015)
    Tumour-initiating cells are known to share some properties with stem cells. These so called 'Cancer Stem Cells' (CSCs) are highly tumourigenic in the undifferentiated state, a property that is lost upon CSC differentiation. ...
  • Investigation of autoantibody profiling to reveal biomarkers of ovarian cancer 

    Murphy, Mairead Anne (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2013)
    Ovarian cancer is the most deadly gynaecological malignancy and 70% of all women with ovarian cancer die within 5 years of diagnosis. When diagnosed in early stages, ovarian cancer is curable in 90% of cases, however early ...
  • ECHO: the epidemiology of HPV infection in oropharyngeal, oral cavity, and laryngeal cancer in Ireland 

    SHARKEY OCHOA, IMOGEN (Trinity College Dublin. School of Medicine. Discipline of Histopathology, 2019)
    Human Papillomavirus (HPV) infection has been identified as a significant etiological agent in the development of head and neck squamous cell carcinoma (HNSCC). There is mounting evidence from North America and Europe to ...
  • Molecular analysis of Human Herpes Virus 8 and associated lesions 

    Silva, Ivan (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2003)
    This thesis looks at the bio-pathways of HHV8 through the transformation of endothelial cell lines. This was performed in two separate but mutually contributing experiments. First, endothelial cell lines were infected using ...

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