Recent Submissions

  • Human papillomavirus prevalence in the Irish cervical screening population and a specific group of HIV positive women 

    Mc Inerney, Jamie Kevin (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2011)
    Human Papillomavirus (HPV) is the major aetiological agent in the development of cervical pre-cancer and cancer with high-risk HPV (HR-HPV) types 16 and 18 detected in greater than 70% of squamous cell carcinomas of the ...
  • Identification of novel biomarkers in recurrent / chemoresistant ovarian cancer 

    Laios, Alexandros (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2009)
    The aim of this study was to identify novel biomarkers in recurrent/chemoresistant ovarian cancer, yet an incurable disease. Using cDNA microarrays, we identified distinct patterns of gene expression between primary and ...
  • Post-transcriptional Dysregulation by microRNAs is implicated in the Pathogenesis of Gastrointestinal Stromal Tumour [GIST] 

    Kelly, Lorna Catherine-Noelle (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2013)
    In a cohort of 73 GISTs including adult mutant, adult wild-type and paediatric cases miRNA expression was examined using TaqMan® Low Density Arrays (TLDAs), allowing the profiling of 667 miRNAs in a set of two (pool A and ...
  • The p16INK4A pathway in cervical cancer 

    Kehoe, Louise (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2010)
    The p16INK4A protein has been proposed as a biomarker in cervical cancer and pre-cancer. p16INK4A over expression is in contrast to that seen in other cancers, where locus deletion or mutation is the norm. p16INK4A is ...
  • The role of activated RET in papillary tumour morphogenesis 

    Flavin, Richard (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2011)
    RET/PTC rearrangements are initiating events in the development of a significant proportion of papillary thyroid carcinomas. Activated RET/PTC mutations are thought to be restricted to thyroid disease, but in this study ...

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