Browsing Haematology (Scholarly Publications) by Subject "platelet activation"

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  • Platelet factor 4 impairs the anticoagulant activity of activated protein C. 

    PRESTON, ROGER; HARMON, SHONA; NI AINLE, FIONNUALA; O'DONNELL, JAMES; JOHNSON, JENNIFER (2009)
    Platelet factor 4 (PF4) is an abundant platelet -granule chemokine released following platelet activation. PF4 interacts with thrombomodulin and the -carboxyglutamic acid (Gla) domain of protein C, thereby enhancing ...