Browsing Haematology (Scholarly Publications) by Author "Zisterer, Daniela"
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A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma
Mc Elligott, Tony; Rozas, Isabel; Zisterer, Daniela; Hayden, Patrick; Lynam-Lennon, Niamh; Browne, Paul (2022)Aims: We have recently described a novel guanidinium-based compound, VP79s, which induces cytotoxicity in various cancer cell lines. Here, we aim to investigate the activity of VP79s and associated mechanisms of action in ...