Chemistry (Theses and Dissertations): Recent submissions
Now showing items 1-20 of 395
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Exploring the Diverse Landscape of Layered Double Hydroxide-Based Nanomaterials
(Trinity College Dublin. School of Chemistry. Discipline of ChemistryTrinity College Dublin, School of Chemistry, 2024)This thesis details the synthesis, characterisation, and an exploration of the diverse application landscape of layered double hydroxide (LDH)-based nanomaterials. The aim is to showcase the potential of LDHs in chirality ... -
Nucleoside and Oligonucleotide Modification for Targeting the DNA Damage Repair Enzyme SNM1A
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The exonuclease SNM1A is a key enzyme involved in the repair of interstrand crosslinks, a highly cytotoxic form of DNA damage. As cells depleted in this enzyme display increased sensitivity to chemotherapeutic agents such ... -
Tailored nitrogen-containing polyaromatics - from surfaces to stacks
(Trinity College (Dublin, Ireland). School of Chemistry, 2016)Chapter 1: This chapter gives a broad introduction to the subjects of graphene and nanographenes, which are discussed in subsequent chapters. Common methodologies for the synthesis of substituted polyphenylenes and ... -
Thiol-Ene "Click" A Radical Tool for Chemoselective Modification and Labelling of Biomolecules
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2023)Thiol-Ene Click chemistry represents a venerable reaction in chemical synthesis, allowing the efficient formation of a sulfur-carbon bond from thiol and alkene reaction partners. This reaction has found myriad applications ... -
Organocatalysis by halogen bonding donors: A promising complement to hydrogen bond-based catalysis.
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2023)Catalytic transformations, previously dominated by metal catalysts, have seen exponential growth in the use of organocatalysts over the last two decades. The emergence of small organic molecules employed to facilitate ...