Browsing Chemistry (Theses and Dissertations) by Title
Now showing items 60-79 of 394
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Design and characterization of functional interfaces for fundamental studies of nitro-polycyclic aromatic hydrocarbon chemistry
(Trinity College (Dublin, Ireland). School of Chemistry, 2014)Nitro-polycyclic hydrocarbons (nPAHs) are a class of highly mutagenic compounds whose reactions and fates in the atmosphere have a tremendous effect on atmospheric chemistry. In the troposphere, the photodegradation of ... -
Design and development of novel self-assembled luminescent lanthanide complexes in solution and in soft materials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, School of Chemistry, 2017)This thesis describes the design, synthesis and characterisation of naphthyl-dipicolylamide (naphthyl-dpa) ligands for sensitisation of lanthanide, Ln(III), emission. Chapter 1 provides an introduction to the fundamental ... -
Design and synthesis of DMAP-derived organocatalysts for enantioselective induction
(Trinity College (Dublin, Ireland). School of Chemistry, 2007)The development of small organic molecules capable of mimicking enzymatic action (in an asymmetric catalysis context) is a challenge that is receiving widespread attention in contemporary organic chemistry. Herein we report ... -
Design and Synthesis of Meso- and Macrocyclic Tripodal Triamine Ligands and Investigations into their Coordination Chemistry
(Trinity College (Dublin, Ireland). School of Chemistry, 2017)The ability to directly and selectively functionalise hydrocarbons is one of the greatest remaining challenges facing chemists. The development of catalytic systems capable of affecting these transformations under ambient ... -
Design and Synthesis of Terpyridine Functionalised Supramolecular Architectures
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)Coordination-driven supramolecular assembly is an extremely useful tool to generate architectures of increased complexity and functionality, such as metallo-supramolecular gels and emissive materials. Interest in the ... -
Design of a novel family of bifunctional phase-transfer catalysts and their applications in the kinetic resolution of 2-oxindole derivatives
(Trinity College (Dublin, Ireland). School of Chemistry, 2015)The design and synthesis of a biomimetic organocatalyst mimicking the active site of aspartate proteases have been undertaken. The design was aimed at constructing an artificial enzyme bearing two carboxylic acid groups ... -
The Design of Ruthenium and Iridium Triplet Photosensitisers
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2023)This thesis describes compounds designed to harness the energies of photon-induced transitions between electronic energy levels. Applications that involve such transitions include but are not limited to photodynamic therapy, ... -
Design, synthesis and pharmacological evaluation of novel heterocyclic guanidine derivatives as alpha₂-adrenoceptor antagonists for the treatment of depression
(Trinity College (Dublin, Ireland). School of Chemistry, 2012)Messages travel through the brain and nervous system in two ways, the first is in the form of an electrical impulse, called an action potential, which travels along a cell called a neuron. The second is via a chemical ... -
Design, synthesis and photophysical evaluation of novel 1 ,8-naphthalimide Tröger's base derivatives
(Trinity College (Dublin, Ireland). School of Chemistry, 2012)This thesis entitled 'Design, Synthesis and Photophysical Evaluation of Novel 1,8- Naphthalimide Based Troger's Bases' is divided into five chapters. The first chapter provides a brief description of the structure of DNA ... -
Design, synthesis and photophysical evaluation of novel luminescent sensing devices : from anion sensors to heteroditopic receptors
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)This thesis entitled "Design, Synthesis and Photophysical Evaluation of Novel Luminescent Sensing Devices: From Anion Sensors to Heteroditopic Receptors" is divided into six chapters. Chapter 1, the introduction, is divided ... -
Design, synthesis and physical evaluation of luminescent lanthanide-based supramolecular systems
(Trinity College (Dublin, Ireland). School of Chemistry, 2007)This thesis entitled "Design, Synthesis and Physical Evaluation of Luminescent Lanthanide-based Supramolecular Systems" is divided into five chapters, and is in two parts. The first part. Chapter 2, deals with the synthesis ... -
Design, synthesis, and biochemical evaluation of guanidine-based derivatives targeting protein kinases
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Kinases are some of the most intensively pursued classes of drug targets with approximately 243 distinct kinase inhibitors making it to human trials and most of these compounds are being investigated for the treatment of ... -
Design, synthesis, photophysical and biological evaluation of Novel 1,8-naphthalimide derivatives as DNA binders and potential anti-cancer agents
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)This thesis, titled 'Design, Synthesis, Photophysical and Biological Evaluation of Novel 1,8-Naphthalimide Derivatives As DNA Binders and Potential Anti-Cancer Agents' is divided into seven chapters. The first chapter is ... -
Designer Nonplanar Porphyrins with Tuned Properties for Application as Bifunctional Organocatalyst
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)The aim of this research was to investigate the use of different free base nonplanar porphyrins as bifunctional catalysts. This involved the tailored design of various porphyrin catalysts and the subsequent testing of said ... -
Developing 1,10-phenanthroline complexes towards their application as triplet sensitizers
(Trinity College (Dublin, Ireland). School of Chemistry, 2014)Summary - Chapter 1: This chapter begins with a general introduction to polycyclic aromatic hydrocarbons, followed by a focused review of recent 3,8-substituted 1,10-phenanthroline systems reported in the literature. The ... -
Developing state of the art sample preparation for high-resolution electron microscopy
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)In recent years there have been great advances in scanning transmission electron microscopes, in particular, high-resolution low voltage imaging and high-resolution electron energy loss spectroscopy. These techniques rely ... -
Development and investigation of novel transition metal mediated reactions in porphyrin chemistry
(Trinity College (Dublin, Ireland). School of Chemistry, 2009)The aim of this work was to extend the number of existing pathways for the synthesis of porphyrins. The focus was directed towards the development and investigation of new transition metal catalysed reactions in porphyrin ... -
Development and Studies of New Magnetic Core@Shell Nanostructures
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)In this work, the synthesis of various magnetic nanoparticles such as magnetite, manganese ferrite, cobalt ferrite and copper ferrite is explored using different synthetic protocols. The produced nanomaterials are characterised ... -
Development of 2D Nanomaterials Based Membranes for Nanofiltration Applications
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)The main aim of this work was to develop new membranes based on 2D nanomaterials, such as boron nitride (BN) and molybdenum disulphide (MoS2) for potential nanofiltration applications. The exfoliation and membrane preparation ... -
Development of a robust throughput process for the production of PMMA membranes via a TIPS air casting method
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)Lateral flow membranes (membranes that allow movement of fluid across the membrane rather than through it) play a crucial role in the functionality of immunoassay devices determining performance speed and assay reliability. ...