Browsing Zoology by Author "STAFFORD, PETER"
Now showing items 1-7 of 7
- Sort by:
- title
- issue date
- submit date
- Order:
- ascending
- descending
- Results:
- 5
- 10
- 20
- 40
- 60
- 80
- 100
-
The development of a mouse model to explore resistance and susceptibility to early Ascaris suum infection
HOLLAND, CELIA; STAFFORD, PETER (2006)Ascaris suum and Ascaris lumbricoides exhibit an over-dispersed frequency distribution in their host populations in both the adult and larval stages. The impact of host factors on this observed distribution is still poorly ... -
Dose-dependent impact of larval Ascaris suum on host body weight in the mouse model
HOLLAND, CELIA; STAFFORD, PETER (2009)Ascaris lumbricoides and Ascaris suum are important helminth parasites of humans and pigs, respectively. Although it is now well established that the presence of mature adult worms in the host intestine contributes to ... -
Genetic influence on the kinetics and associated pathology of the early stage (intestinal-hepatic) migration of Ascaris suum in mice
HOLLAND, CELIA; STAFFORD, PETER (2010)The generative mechanism(s) of aggregation and predisposition to Ascaris lumbricoides and A. suum infections in their host population are currently unknown and difficult to elucidate in humans and pigs for ethical/logistical ... -
The influence of inoculum size and time post-infection on the number and position of Toxocara canis larvae recovered from the brains of outbred CD1 mice
HOLLAND, CELIA; STAFFORD, PETER (2001)Outbred CD1 mice were administered doses of 1000 and 3000 Toxocara canis eggs and postmortem took place on days 7, 42 and 120 post-infection. Mice were killed by cervical dislocation and brains were sagitally bisected and ... -
The migration of Ascaris suum larvae, and the associated pulmonary inflammatory response in susceptible C57BL/6j and resistant CBA/Ca mice
HOLLAND, CELIA; STAFFORD, PETER (2007)Ascariasis is an important infection in humans (Ascaris lumbricoides) and pigs (Ascaris suum) and individuals appear to be predisposed to either heavy or light worm burdens. These extremes of susceptibility and resistance ... -
A murine model for cerebral toxocariasis: characterisation of host susceptibility and behaviour.
HOLLAND, CELIA; STAFFORD, PETER (2006)Toxocara canis, the parasitic roundworm of dogs, can infect a number of paratenic hosts, such as mice and humans, due to the widespread dissemination of its ova in the environment. In these paratenic hosts, larvae have ... -
The role of Intelectin-2 in resistance to Ascaris suum lung larval burdens in susceptible and resistant mouse strains
HOLLAND, CELIA; STAFFORD, PETER (2011)The underlying mechanism of predisposition to Ascaris infection is not yet understood but host genetics are thought to play a fundamental role. We investigated the association between the Intelectin-2 gene and resistance ...