Browsing Surgery (Scholarly Publications) by Author "O'BYRNE, KEN"
Now showing items 1-4 of 4
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COX-Derived prostanoid pathways in gastrointestinal cancer development and progression: Novel targets for prevention and intervention
REYNOLDS, JOHN; O'SULLIVAN, JACINTHA; CATHCART, MARY CLARE; PIDGEON, GRAHAM; O'BYRNE, KEN (Elsevier, 2012)Arachidonic acid metabolism through cyclooxygenase (COX) pathways leads to the generation of biologically active eicosanoids. Eicosanoid expression levels vary during development and progression of gastrointestinal (GI) ... -
Modern operative and oncological outcome in oesophagel cancer
REYNOLDS, JOHN; DONOHOE, CLAIRE; HOLLYWOOD, DONAL; O'BYRNE, KEN; RAVI, NARAYANASAMY (2011) -
The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer
PIDGEON, GRAHAM; REYNOLDS, JOHN; O'BYRNE, KEN (2010)Prostacyclin synthase and thromboxane synthase signaling via arachidonic acid metabolism affects a number of tumor cell survival pathways such as cell proliferation, apoptosis, tumor cell invasion and metastasis, and ... -
Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer
GATELY, KATHY; O'BYRNE, KEN; PIDGEON, GRAHAM; GRAY, STEVEN (2015)Background: The VEGF pathway has become an important therapeutic target in lung cancer, where VEGF has long been established as a potent pro-angiogenic growth factor expressed by many types of tumors. While Bevacizumab ...