Browsing Surgery (Scholarly Publications) by Author "LYSAGHT, JOANNE"
Now showing items 1-4 of 4
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Elevated Tumor Expression of PAI-1 and SNAI2 in Obese Esophageal Adenocarcinoma Patients and Impact on Prognosis.
LYSAGHT, JOANNE; REYNOLDS, JOHN; PIDGEON, GRAHAM (2012) -
Heat shock protein derived from a non-autologous tumour can be used as an anti-tumour vaccine.
LYSAGHT, JOANNE (2003)Antigenic cross-reactivity between certain tumours has allowed the development of more widely applicable, major histocompatibility complex-disparate (allogeneic) whole-cell vaccines. This principle should also allow heat ... -
Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue
ALLOTT, EMMA; PIDGEON, GRAHAM; LYSAGHT, JOANNE; REYNOLDS, JOHN; DONOHOE, CLAIRE; HOWARD, JULIA MARY; RAVI, NARAYANASAMY; CASEY, RORY (2011)Obesity has been associated with increased incidence and mortality of oesophageal and colorectal adenocarcinoma. Excess central adiposity may drive this association through an altered inflammatory milieu. Utilizing a unique ... -
Targeting T cell immunometabolism for cancer immunotherapy; understanding the impact of the tumor microenvironment.
O'NEILL, LUKE; LYSAGHT, JOANNE; CONROY, MELISSA (2014)The immune system has a key role to play in controlling cancer initiation and progression. T cell activation, which is central to anti-tumor immune responses, coincides with changes in cellular metabolism. Naïve T cells ...