RSS 1.0Radiation Therapy (Theses and Dissertations)
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Magnetic Resonance Imaging Radiomics - Towards the Personalisation of Radiation Therapy for Prostate Cancer.
(Trinity College Dublin. School of Medicine. Discipline of Radiation Therapy, 2020)The primary function of a predictive biomarker is to accurately determine the outcome of a specified treatment. Radiomics is a developing field that involves advanced image analysis and high throughput extraction of ... -
The development, implementation and evaluation of frailty assessment in oncology
(Trinity College Dublin. School of Medicine. Discipline of Radiation Therapy, 2020)Over the last number of decades, treatment outcomes from cancer care have improved dramatically. However, these improvements have mostly benefitted younger patients, or relatively robust older adults, rather than the entire ... -
In vitro modelling of androgen-mediated gene-directed enzyme prodrug therapy for the treatment of prostate cancer
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Radiation Therapy, 2012)Gene-directed enzyme prodrug therapy has the potential to improve prostate cancer therapy outcome and could be used on its own or as an adjuvant to the current treatments. This research involved the characterisation of a ... -
DNA mismatch repair and low dose hyper-radiosensitivity in prostate cancer cells
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Radiation Therapy, 2010)Low-dose hyper-radiosensitivity (HRS) describes the excessive sensitivity of cells to radiation doses less than 0.3Gy. Evidence suggests that HRS may influence tumour response and normal tissue reactions after intensity ... -
Radiation oncology safety information system (ROSIS) : a reporting and learning system for radiation oncology
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Radiation Therapy, 2011)Background and Purpose: Incident reporting is a recognised tool for learning from incidents. The Radiation Oncology Safety Information System (ROSIS) was established in 2001, to collate and share information on incidents ...
