Visualisation and simulation of myocardial infarctions from 12-lead ECG

Abstract

Myocardial Infarction (Ml) is one of the main causes of death throughout the world. More commonly known as heart attack, it is caused by the occlusion of one or more of the arteries that supply the heart. Cardiac enzymes found through blood analysis are frequently used to estimate infarct size. The peak creatine kinase (CK) enzyme or troponin (Tn) protein are widely used to determine prognosis and treatment. Non-invasive imaging techniques are also frequently used in clinical practice to determine infarct size and location. These techniques all rely on skilled operators to interpret the images generated. In this thesis, we describe a simple technique for non-invasive assessment of myocardial infarct size and location by generating a 3 dimensional representation of the infarct location from the surface electrocardiograph (ECG).