MicroRNA regulation of the bovine mammary immune response to a mastitis pathogen

Abstract

Bovine mastitis is an inflammation-driven disease of the mammary gland that is associated with €2 billion in yearly losses to the European dairy industry. Streptococcus uberis is now ranked amongst the most prevalent mastitis-causing pathogens throughout the EU and in North America. Mastitis develops when bacteria on entering the mammary gland, encounter mammary epithelial cells and resident monocytes, triggering local and systemic inflammation.