The Measurement of Spatially-Dependant Tissue Sodium Concentration Increase in a Rodent MCAO Stroke Model

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F. Wetterling, S. Junge, A. Nauerth, I.M. Macrae, .A.J. Fagan, The Measurement of Spatially-Dependant Tissue Sodium Concentration Increase in a Rodent MCAO Stroke Model, ISMRM 17th Scientific Meeting, Honolulu, USA, 18-24th April, 2009

Abstract

The aim of this study was to accurately quantify changes in the Tissue Sodium Concentration (TSC) in the acute phase of a rodent stroke model with high spatio-temporal resolution (0.38mm3 / 10min) at 7T. The ability to accurately quantify subtle changes in TSC could provide a marker for tissue viability in stroke [1]. However, the quantification accuracy is limited by the typical low SNR’s arising from the inherently low TSC, fast signal decay and low gyro-magnetic ratio of sodium.

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Author's Homepage: http://people.tcd.ie/wetterf
Other Titles: ISMRM 17th Scientific Meeting
Type of material: Poster