The cost-effectiveness of radiofrequency ablation for Barrett's esophagus with low-grade dysplasia: Results from a randomized controlled trial (SURF trial)

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Phoa K.N, Rosmolen W.D, Weusten B.L.A.M, Bisschops R, Schoon E.J, Das S, Ragunath K, Fullarton G, DiPietro M, Ravi N, Tijssen J.G.P, Dijkgraaf M.G.W, Bergman J.J.G.H.M, The cost-effectiveness of radiofrequency ablation for Barrett's esophagus with low-grade dysplasia: Results from a randomized controlled trial (SURF trial), Gastrointestinal Endoscopy, 2016, 1--

Abstract

Background and Aims The Surveillance versus Radiofrequency Ablation (SURF) trial randomized 136 patients with Barrett's esophagus (BE) containing low-grade dysplasia (LGD), to receive radiofrequency ablation (ablation, n = 68) or endoscopic surveillance (control, n = 68). Ablation reduced the risk of neoplastic progression to high-grade dysplasia and esophageal adenocarcinoma (EAC) by 25% over 3 years (1.5% for ablation vs 26.5% for control). We performed a cost-effectiveness analysis from a provider perspective alongside this trial.

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Author's Homepage: http://people.tcd.ie/ravin
Type of material: Journal Article