Formation of Polysubstituted Pyridin-2-one Derivatives by Michael Addition of 3-Oxobutanamide to ?,?-Ethylenic Ketones and Amides

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O'Callaghan, C.N., McMurry, T.B.H., O'Brien, J.E., Draper, S.M., Gormley, F.K., Formation of Polysubstituted Pyridin-2-one Derivatives by Michael Addition of 3-Oxobutanamide to ?,?-Ethylenic Ketones and Amides , Journal of Chemical Research - Part S, 2, 1997, 50, 51

Abstract

Reaction of 3-oxobutanamide with 4-phenylbut-3-en-2-one and with 3-aryl-2-cyanoprop-2-enamides and related compounds affords new di-, tetra- and hexa-hydropyridin-2-one derivatives, the degree of unsaturation of the product depending on the experimental conditions.

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Type of material: Journal Article