Role of membrane lipids and plasma lipoproteins in the regulation of activated protein C function

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Trinity College (Dublin, Ireland). School of Medicine. Discipline of Haematology

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Jennifer Johnson, 'Role of membrane lipids and plasma lipoproteins in the regulation of activated protein C function', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Haematology, 2013, pp 201

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Activated protein C (APC) is an important anticoagulant factor that serves to downregulate thrombin generation. APC also has several cytoprotective properties, including anti-apoptotic and endothelial barrier stabilizing signalling. This study aimed to investigate the role of lipids in mediating the APC pathway.

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Qualification name: Doctor of Philosophy (Ph.D.)
Publisher: Trinity College (Dublin, Ireland). School of Medicine. Discipline of Haematology
Type of material: thesis