• Immediate-Early-Gene (IEG) expression in excitotoxicity

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    Rogers TCD THESIS 7520 Immediate Early Gene.pdf (305.56 MB)

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    2004

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    Trinity College (Dublin, Ireland). School of Biochemistry and Immunology

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    Annamarie Rogers, 'Immediate-Early-Gene (IEG) expression in excitotoxicity', [thesis], Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2004, pp 427

    Abstract

    The mouse cerebellar granule cell system (mCGCs; Schousboe et al, 1989) was established in this laboratory (Bayer AG, Germany) as a suitable cell culture model for excitotoxicity studies. Suitability was confirmed by MTT-based cytotoxicity, which was induced by glutamate (Glu) receptor agonists and inhibited by NMDA receptor antagonists (APS), but not by antagonists of the non-NMDA receptor subtype (CNQX).

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    http://hdl.handle.net/2262/86598

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    Biochemistry (Theses and Dissertations)
    Trinity College Dublin Theses & Dissertations

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    Biochemistry, Ph.D., Ph.D. Trinity College Dublin

    Author: Rogers, Annamarie

    Qualification name: Doctor of Philosophy (Ph.D.)
    Publisher: Trinity College (Dublin, Ireland). School of Biochemistry and Immunology
    Type of material: thesis