Kinetic resolution of sec-alcohols using a new class of readily assembled (S)-proline-derived 4-(pyrrolidino)-pyridine analogues

CONNON, STEPHEN

doi:http://dx.doi.org/10.1039/b419335k

Kinetic resolution of sec-alcohols using a new class of readily assembled (S)-proline-derived 4-(pyrrolidino)-pyridine analogues

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Kinetic resolution of sec-alcohols using a new class of readily assembled (S)-proline-derived 4-(pyrrolidino)-pyridine analogues.pdf (155.84 KB)

Date

2005

Authors

CONNON, STEPHEN

Citation

C. Ó Dálaigh, S. J. Hynes, D. J. Maher and S. J. Connon, Kinetic resolution of sec-alcohols using a new class of readily assembled (S)-proline-derived 4-(pyrrolidino)-pyridine analogues, Organic and Biomolecular Chemistry, 3, 6, 2005, 981, 984

Abstract

We report the development of a new class of readily prepared chiral 4-(pyrrolidino)-pyridine catalysts capable of exploiting both van der Waals (?) and H-bonding interactions, thus allowing remote chiral information to stereochemically control the kinetic resolution of sec-alcohols.