Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer.

Marignol, Laure; Leech, Michelle

doi:http://dx.doi.org/10.1016/j.apradiso.2015.07.044

Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer.

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Limetal.2015.pdf (641.39 KB)

Date

2015

Authors

Marignol, Laure

Leech, Michelle

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openAccess

Citation

Lim D, Quah DS, Leech M, Marignol L, Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer., Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2015

Abstract

This review compares the safety and efficacy of boron neutron capture therapy (BNCT) in the treatment of previously irradiated, inoperable locoregional recurrent HNC patients and compares BNCT against the standard treatment of platinum-based chemotherapy. Our analysis of published clinical trials highlights efficacy of BNCT associated with mild side effects. However, the use of BNCT should be explored in stratified randomised trials.