• Innate DNA Sensing Moves to the Nucleus

    Thumbnail Image

    Files

    Unterholzner Bowie CHM preview author version.pdf (143.27 KB)

    Date

    2011

    Authors

    Journal Title

    Journal ISSN

    Volume Title

    Publisher

    Access

    OpenAccess

    Embargo end date

    Citation

    Unterholzner, L. & Bowie, A.G., Innate DNA Sensing Moves to the Nucleus, Cell Host and Microbe, 9, 2011, 351 - 353

    Abstract

    It has been assumed that cells distinguish viral from cellular DNA due to the former's presence in the cytosol. However, in this issue, Kerur et al. (2011) propose that the DNA genome of Kaposi's sarcoma-associated herpesvirus (KSHV) is recognized inside the nucleus by the DNA sensor IFI16, leading inflammasome activation

    Description

    PUBLISHED

    URI

    http://hdl.handle.net/2262/68042

    Collections

    Biochemistry (Scholarly Publications)
    Load more

    Endorsement

    Review

    Supplemented By

    Referenced By

    Keywords

    Kaposi's sarcoma-associated herpesvirus (KSHV)

    Sponsor: Science Foundation Ireland (SFI)

    Author's Homepage: http://people.tcd.ie/agbowie

    Author: BOWIE, ANDREW

    Type of material: Journal Article