Investigation of microtubule inhibitors as potential antimalarial agents

Abstract

Malaria is a parasitic infection of immense global importance. The most common and severe form of the disease is caused by the blood-bome apicomplexan parasite Plasmodium falciparum. The lack of an effective vaccine coupled with the emergence and spread of resistance to currently-used antimalarial agents highlights the need for the discovery and development of novel antimalarial drugs.