Derivation of iPSC lines from three young healthy donors of Caucasian origin (NUIGi035-A; NUIGi036-A; NUIGi037-A)
Citation:
Ding, Y., de la Cruz, B.M., McInerney, V., Lu, Y., Yang, G., Qian, X., Li, W., Krawczyk, J., Howard, L., O'Brien, T., Gallagher, L., Shen, S., Derivation of iPSC lines from three young healthy donors of Caucasian origin (NUIGi035-A; NUIGi036-A; NUIGi037-A), Stem Cell Research, 2020 Dec;49:102101Download Item:
Abstract:
The induced pluripotent stem cell (iPSC) technology has offered an unprecedented opportunity for disease modelling and drug discovery. Here we used non-integrating Sendai viral method and derived iPSCs from three young healthy Caucasian donors. All iPSCs expressed pluripotency markers highly and could be differentiated into three germ lineages. They possess normal karyotype which was confirmed by whole genome SNP array. The availability of the healthy control iPSCs offers an opportunity for phenotypic comparison and genome editing for a variety of diseases.
Sponsor
Grant Number
Science Foundation Ireland
13/IA/1787
Author's Homepage:
http://people.tcd.ie/lgallagh
Author: Gallagher, Louise
Type of material:
Journal ArticleCollections
Series/Report no:
Stem Cell Research;49;
102101;
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Full text availableDOI:
http://dx.doi.org/10.1016/j.scr.2020.102101Metadata
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