Browsing Trinity College Dublin Theses & Dissertations by Author "Kane, Kelly"
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Rational design of artificial genetic switches : co-option of H-NS-repressed operons by the VirB virulence master regulator
Kane, Kelly (Trinity College (Dublin, Ireland). School of Genetics and Microbiology, 2012)The H-NS protein represses the transcription of hundreds of genes in Gram-negative bacteria. De-repression is achieved by a multitude of mechanisms, many of which involve binding of a protein to DNA at the repressed promoter ...