Browsing School of Pharmacy and Pharmaceutical Sciences by Title
Now showing items 241-260 of 640
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Freeze drying of polyelectrolyte complex nanoparticles: Effect of nanoparticle composition and cryoprotectant selection
(2018)This work investigates the impact of nanoparticle (NP) composition and effectiveness of cryo-/lyo-protectants in a freeze drying process, which was employed to convert liquid dispersions of polyelectrolyte complex (PEC) ... -
Functional expression of the epithelial sodium channel δ-subunit in human respiratory epithelial cells
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2012)Mammalian amiloride-sensitive epithelial Na+ channel (ENaC) can be composed by different combinations of four homologous subunits, α, β, γ and δ. The canonical αβγ- ENaC, abundantly expressed in Na+ absorbing epithelia, ... -
The future of Extracellular Vesicles as Theranostics - an ISEV meeting report
(2020)The utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in the past decade. In November 2018, the International Society for Extracellular Vesicles (ISEV) held a workshop on “EVs in ... -
Gene expression analysis of mouse embryonic stem cells following levitation in an ultrasound standing wave trap.
(2011)In the present paper, gene expression analysis of mouse embryonic stem (ES) cells levitated in a novel ultrasound standing wave trap (USWT) (Bazou et al. 2005a) at variable acoustic pressures (0.08?0.85 MPa) and times ... -
Gene Expression Profiling
(Humana Press, 2009) -
Generic Drugs
(2008) -
Genetic Polymorphisms in the Histamine Receptor Family
(Humana Press, Springer Nature, 2016)Histamine is a biogenic amine which has an inherent biological importance in many physiological functions, both in the central nervous system and in the periphery. With the new genomic era we are facing, personalized care ... -
Green Synthesis of Lidocaine Ionic Liquids and Salts: Mechanisms of Formation and Interactions in the Crystalline and Supercooled States
(2020)Mechanochemistry has been recognized as an optimal route for the synthesis of ionic liquids incorporating active pharmaceutical ingredients (API-ILs) as it eliminates the need for large volumes of solvents and purification ... -
The Gut-Brain Axis in Inflammatory Bowel Disease: Assessment of the Central Inflammatory Response to Dextran Sulfate Sodium-Induced Colitis in Rats
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2018)Inflammatory bowel disease (IBD) is a chronic relapsing-remitting inflammatory condition of the gastrointestinal (GI) tract. Evidence indicates a comorbidity between IBD and psychological symptoms in patients. It is thought ... -
Heat induced evaporative antisolvent nanoprecipitation (HIEAN) of itraconazole.
(2014)traconazole (ITR) is an antifungal drug with a limited bioavailability due to its poor aqueous solubility. In this study, ITR was used to investigate the impact of nanonisation and solid state change on drug's apparent ... -
High-Pressure Dielectric Studies-a Way to Experimentally Determine the Solubility of a Drug in the Polymer Matrix at Low Temperatures
(2021)In this work, we employed broad-band dielectric spectroscopy to determine the solubility limits of nimesulide in the Kollidon VA64 matrix at ambient and elevated pressure conditions. Our studies confirmed that the solubility ... -
Hormonal and emotional regulation of memory processes
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2003)This thesis comprises two areas of study. The first study examined the effect of the menstrual cycle on Event-Related Potentials (ERPs) and verbal memory, as measured by paragraph recall and paired associates, and mood, ... -
Hospital Pharmacy in Ireland
(Pharmaceutical Society of Ireland, 2012) -
HPLC profiling of Mimosa pudica polyphenols and their non-invasive biophysical investigations for anti-dermatoheliotic and skin reinstating potential
(2019)Plant-derived polyphenols are known to have promising biological activities including antioxidant and anti-tyrosinase and may be a potential candidate for anti-dermatoheliotic remedy. The present study was performedto ...