dc.contributor.author | O'MARA, SHANE | en |
dc.contributor.author | PASSECKER, JOHANNES | en |
dc.contributor.author | CHAH, EHSAN | en |
dc.contributor.author | DELLA CHIESA, ANDREA | en |
dc.contributor.author | HOK, VINCENT | en |
dc.date.accessioned | 2011-11-07T14:19:16Z | |
dc.date.available | 2011-11-07T14:19:16Z | |
dc.date.issued | 2011 | en |
dc.date.submitted | 2011 | en |
dc.identifier.citation | Passecker J, Hok V, Della-Chiesa A, Chah E, O'Mara SM, Dissociation of dorsal hippocampal regional activation under the influence of stress in freely behaving rats., Frontiers in Behavioral Neuroscience, 5, 2011, 66- | en |
dc.identifier.issn | 1662-5153 | en |
dc.identifier.other | Y | en |
dc.identifier.uri | http://hdl.handle.net/2262/60551 | |
dc.description | PUBLISHED | en |
dc.description.abstract | Stress has deleterious effects on brain, body, and behavior in humans and animals alike. The present work investigated how 30-min acute photic stress exposure impacts on spatial information processing in the main sub-regions of the dorsal hippocampal formation [CA1, CA3, and dentate gyrus (DG)], a brain structure prominently implicated in memory and spatial representation. Recordings were performed from spatially tuned hippocampal and DG cells in rats while animals foraged in a square arena for food. The stress procedure induced a decrease in firing frequencies in CA1 and CA3 place cells while sparing locational characteristics. In contrast to the CA1-CA3 network, acute stress failed to induce major changes in the DG neuronal population. These data demonstrate a clear dissociation of the effects of stress on the main hippocampal sub-regions. Our findings further support the notion of decreased hippocampal excitability arising from behavioral stress in areas CA1 and CA3, but not in DG. | en |
dc.format.extent | 66 | en |
dc.language.iso | en | en |
dc.relation.ispartofseries | Frontiers in Behavioral Neuroscience | en |
dc.relation.ispartofseries | 5 | en |
dc.rights | Y | en |
dc.subject | Neuroscience | en |
dc.subject | Stress | en |
dc.title | Dissociation of dorsal hippocampal regional activation under the influence of stress in freely behaving rats. | en |
dc.type | Journal Article | en |
dc.type.supercollection | scholarly_publications | en |
dc.type.supercollection | refereed_publications | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/smomara | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/hokv | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/dellacha | en |
dc.identifier.rssinternalid | 75725 | en |
dc.identifier.doi | http://dx.doi.org/10.3389/fnbeh.2011.00066 | en |
dc.subject.TCDTheme | Neuroscience | en |
dc.identifier.rssuri | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194099/?tool=pubmed | en |
dc.identifier.orcid_id | 0000-0001-8087-8531 | en |
dc.contributor.sponsor | Science Foundation Ireland (SFI) | en |
dc.contributor.sponsorGrantNumber | 8AA G22112 | en |