Genome-wide association studies: a primer.
Item Type:Journal Article
Citation:Corvin A, Craddock N, Sullivan PF., Genome-wide association studies: a primer., Psychological Medicine, 40, 7, 2010, 1063-1077
Genome-wide association studies- a primer.pdf (Published (publisher's copy) - Peer Reviewed) 215.4Kb
There have been nearly 400 genome-wide association studies (GWAS) published since 2005. The GWAS approach has been exceptionally successful in identifying common genetic variants that predispose to a variety of complex human diseases and biochemical and anthropometric traits. Although this approach is relatively new, there are many excellent reviews of different aspects of the GWAS method. Here, we provide a primer, an annotated overview of the GWAS method with particular reference to psychiatric genetics. We dissect the GWAS methodology into its components and provide a brief description with citations and links to reviews that cover the topic in detail.
Author: CORVIN, AIDEN PETER
Publisher:Cambridge University Press
Type of material:Journal Article
Series/Report no:Psychological Medicine;
Availability:Full text available