Genome-wide association studies: a primer.
Citation:
Corvin A, Craddock N, Sullivan PF., Genome-wide association studies: a primer., Psychological Medicine, 40, 7, 2010, 1063-1077Download Item:
Abstract:
There have been nearly 400 genome-wide association studies (GWAS) published since 2005. The GWAS approach has been exceptionally successful in identifying common genetic variants that predispose to a variety of complex human diseases and biochemical and anthropometric traits. Although this approach is relatively new, there are many excellent reviews of different aspects of the GWAS method. Here, we provide a primer, an annotated overview of the GWAS method with particular reference to psychiatric genetics. We dissect the GWAS methodology into its components and provide a brief description with citations and links to reviews that cover the topic in detail.
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http://people.tcd.ie/acorvinDescription:
PUBLISHED
Author: CORVIN, AIDEN PETER
Publisher:
Cambridge University PressType of material:
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Series/Report no:
Psychological Medicine;40;
7;
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Genetics, genome-wide association studies (GWAS)Metadata
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