Browsing School of Medicine by Subject "Haemostasis"
Now showing items 1-3 of 3
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Defining the mechanisms through which von willebrand factor sialic acid expression regulates in vivo clearance
(Trinity College Dublin. School of Medicine. Discipline of Haematology, 2019)Von Willebrand Factor (VWF) is a complex plasma sialoglycoprotein which plays a key role in maintaining normal haemostasis. While the biosynthesis, structure, and functions of VWF are well characterised, the molecular ... -
Investigating the Role of Von Willebrand Factor in Regulating Macrophage Biology and Innate Immunity
(Trinity College Dublin. School of Medicine. Discipline of Haematology, 2019)The plasma multimeric glycoprotein von Willebrand factor (VWF) plays a critical role in primary haemostasis by tethering platelets to exposed collagen at sites of vascular injury. Recent studies have suggested that VWF may ...