Browsing School of Medicine by Title
Now showing items 833-852 of 1176
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Pancreatic anastomosis after pancreatoduodenectomy: A position statement by the International Study Group of Pancreatic Surgery (ISGPS)
(2016)Clinically relevant postoperative pancreatic fistula (grades B and C of the ISGPS definition) remains the most troublesome complication after pancreatoduodenectomy. The approach to management of the pancreatic remnant via ... -
Partners in Learning: An Investigation into a Service-Learning Module for Community Partners and Occupational Therapy Students
(Trinity College Dublin. School of Medicine. Discipline of Occupational Therapy, 2018)Service-learning is a pedagogical approach to learning which aims to link academic coursework to real word situations through the provision of service (Eyler & Giles, 1999). The body of literature concerning service-learning ... -
Pathway specific modulation of S1P1 receptor signalling in rat and human astrocytes.
(2013)BACKGROUND AND PURPOSE: The sphingosine 1-phosphate receptor subtype 1 (S1P1R) is modulated by phosphorylated FTY720 (pFTY720), which causes S1P1R internalization preventing lymphocyte migration thus limiting autoimmune ... -
Patterns of Transcriptional Response to 1,25-Dihydroxyvitamin D3 and Bacterial Lipopolysaccharide in Primary Human Monocytes.
(2016)The active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25D), plays an important immunomodulatory role, regulating transcription of genes in the innate and adaptive immune system. The present study examines patterns of ... -
The PDZ Domain of PICK1 Differentially Accepts Protein Kinase C-α and GluR2 as Interacting Ligands
(2004)The C terminus (ct) of protein kinase C-α (PKCα) has a type I PDZ binding motif, whereas GluR2 has a type II PDZ binding motif. Both motifs are recognized by the PDZ domain of protein interacting with protein kinase C ... -
'Peas in a Pod?' - The body composition of the term and preterm infant
Introduction: Weight has been the primary outcome measure for many studies of both term and preterm infants. Body composition reflects the quality of infant growth. Using air displacement plethysmography, infant body ... -
Peer support for patients with type 2 diabetes: cluster randomised controlled trial.
(2011)OBJECTIVE: To test the effectiveness of peer support for patients with type 2 diabetes. DESIGN: Cluster randomised controlled. SETTING: 20 general practices in the east of the Republic of Ireland. PARTICIPANTS: 395 ... -
Peer support in type 2 diabetes : a radomised controlled trial in primary care
(Trinity College (Dublin, Ireland). Department of Public Health and Primary Care, 2010)Type 2 diabetes has now reached epidemic proportions in many countries. Self management programmes for type 2 diabetes have recently moved away from the traditional didactic interventions to patient empowerment and peer-led ... -
A Peer-Led Survey of Student Alcohol Behaviours and Attitudes in Undergraduate Students
(2021)Background: This study examines Irish undergraduate students’ behaviours and motives regarding alcohol consumption. The study explores both levels and patterns of consumption. Method: A cross-sectional design using a ... -
Performance measures for small-bowel endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative.
(2019)The European Society of Gastrointestinal Endoscopy (ESGE) together with the United European Gastroenterology (UEG) recently developed a short list of performance measures for small-bowel endoscopy (i.e. small-bowel capsule ... -
Perinatal Depression and Children's Developmental Outcomes at 2 and 3 Years Postpartum
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2022)Depression is the most common perinatal psychiatric disorder and has been associated with a range of adverse outcomes for children, parents and overall family functioning. The current thesis sought to build on existing ... -
Peripheral administration of a humanized anti-PrP antibody blocks Alzheimer's disease Aß synaptotoxicity
(2014)Alzheimer's disease (AD) is associated with pathological assembly states of amyloid-β protein (Aβ). Aβ-related synaptotoxicity can be blocked by anti-prion protein (PrP) antibodies, potentially allowing therapeutic targeting ... -
Perspective: Vitamin D supplementation prevents rickets and acute respiratory infections when given as daily maintenance but not as intermittent bolus: Implications for COVID-19
(2021)The value of vitamin D supplementation in the treatment or prevention of various conditions is often viewed with scepticism as a result of contradictory results of randomised trials. It is now becoming apparent that there ...