Browsing School of Medicine by Title
Now showing items 1756-1775 of 3129
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L-Plastin Expression in HCT 116 Colorectal Cells increases migration and ROS in an NADPH Oxidase-dependent manner
(2022)Objective: L-plastin is an action-bundling protein normally expressed in cells of haemopoietic origin but is also associated with malignant transformation. Aberrant expression of L-plastin expression correlates with tumour ... -
Lack Of Association Between Angiotensin-converting Enzyme (Ace) Genotype And Essential Hypertension In Peruvian Older People
(2020)Background: Epidemiological studies have shown an association between the ACE gene I / D polymorphism with arterial hypertension, specifically the DD genotype in different populations. The objective of this study is to ... -
Lack of association between angiotensin-converting enzyme genotype and muscle strength in Peruvian older people
(2020)Aging can be associated with decreasing muscle strength, and related factors are comorbidities, sex, physical activity, and possibly genetic factors. Among genetic factors the renin-angiotensin system is of interest, but ... -
Lack of gender effect on familial schizophrenia. A Brazilian study.
(Arquivos de Neuro Psiquiatria / Academia Brasileira de Neurologia - ABNEURO, 2000)Estudos epidemiologicos em esquizofrenia estabeleceram que a idade de inicio para o genero masculino precede em alguns anos aquela para o feminino. No entanto, tal efeito de genero n?o vem sendo observado para os casos ... -
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism
(2020)We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n = 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to integrate de novo and case-control rare variation, ... -
Laser speckle correlation as a non-contact ocular microtremor measurement technique
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2014)Ocular microtremor (OMT) is high frequency, low amplitude fixational eye movement present in all healthy people. It occurs even while the eye appears to be at rest. Benefits of measuring OMT have been proven in a number ... -
The Lasting Legacy of Childhood Adversity for Disease Risk In Later Life
(2015)Objective: There has been an increased interest in the role of the childhood social environment in the etiology of adult diseases in recent years. The present study examines whether the experience of adversity during ... -
LC3B globular structures correlate with survival in esophageal adenocarcinoma
(2015)Background Esophageal adenocarcinoma has the fastest growing incidence of any solid tumor in the Western world. Prognosis remains poor with overall five-year survival rates under 25 %. Only a limited number of patients ... -
Leadership Capabilities and Challenges in the Physiotherapy Profession in Ireland
(Trinity College Dublin. School of Medicine. Department of Physiology, Trinity College Dublin. School of Medicine. Department of Physiology, 2017)The physiotherapy profession in Ireland is experiencing a period of transition and change and is facing many challenges. The importance of leadership in healthcare has been recognised, however, to date there has been ... -
Learning and decay of prediction in object manipulation.
(2000)Anticipating the consequences of our own actions is a fundamental component of normal sensorimotor control and is seen, for example, during the manipulation of objects. When one hand pulls on an object held in the other ... -
Left atrial invasion by pulmonary adenocarcinoma
(2007)A 72-year-old female presented with haemoptysis. CT thorax demonstrated a right lower lobe mass infiltrating the left atrium (Fig. 1 ). Bronchoscopy and biopsy confirmed endobronchial adenocarcinoma. Left atrial invasion ... -
Left ventricular diastolic function in early hypertension
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics, 2008)This thesis presents the development of clinical applications of the relatively new ultrasound modality, TDI in conjunction with the earlier more established modalities of echocardiography. The contents of this thesis ... -
Legislation for smoke-free workplaces and health of bar workers in Ireland: before and after study
(BMJ Publishing Group, 2005)Objectives: To compare exposure to secondhand smoke and respiratory health in bar staff in the Republic of Ireland and Northern Ireland before and after the introduction of legislation for smoke-free workplaces in the ... -
The length of stay of in-patient stroke discharges in Irish acute hospitals
(2013)Stroke imposes an important economic burden worldwide and acute in-patient care accounts for a large proportion of costs in the first year following stroke. Length of stay (LOS) is regarded as a key determinant of in-patient ... -
Leptin and adiponectin receptor expression in oesophageal cancer.
(2014)BACKGROUND: Oesophageal adenocarcinoma is an exemplar model of an obesity-associated adenocarcinoma. Altered secretion of adipokines by visceral fat is believed to play a key role in tumorigenesis. This study examined ... -
Lessons of ALS imaging: Pitfalls and future directions - A critical review
(2014)Background: While neuroimaging in ALS has gained unprecedented momentum in recent years, little progress has been made in the development of viable diagnostic, prognostic and monitoring markers. Objectives: To identify ...
