Browsing Chemistry by Subject "Halogen bonding"
Now showing items 1-3 of 3
-
An Insight into Non-Covalent Interactions on the Bicyclo[1.1.1]pentane Scaffold
(2021)Bicyclo[1.1.1]pentane (BCP) is studied extensively as a bioisosteric component of drugs. Not found in nature, this molecular unit approximates the distance of a para-disubstituted benzene which is replaced in medicines as ... -
Investigating the Impact of Conformational Molecular Engineering on the Crystal Packing of Cavity Forming Porphyrins
(2019)Herein we report the synthesis of 5,10,15,20-tetraaryl-(X)-substituted- 2,3,7,8,12,13,17,18-octaethylporphyrins (OETArXPs) and a structural investigation of their solid-state properties via small molecule X-ray diffraction. ... -
Not Your Usual Bioisostere: Solid State Study of 3D Interactions in Cubanes
(2019)Previous studies by Desiraju and co-workers have implicated the acidic hydrogen atoms of cubane as a support network for hydrogen-bonding groups. Herein we report a detailed structural analysis of all currently available ...